Univ.-Prof. Dr. Thomas Böttcher
Thomas Böttcher
21 - 40 out of 47
Penalver, L., Schmid, P., Szamosvari, D., Schildknecht, S., Globisch, C., Sawade, K., Peter, C., & Boettcher, T. (2021). A Ligand Selection Strategy Identifies Chemical Probes Targeting the Proteases of SARS-CoV-2. Angewandte Chemie (International Edition), 60(12), 6799-6806. https://doi.org/10.1002/anie.202016113

Boettcher, T. (2020). Unveiling the Hidden Theatre of Microbes. ChemBioChem: a european journal of chemical biology, 21(20), 2869-2869. https://doi.org/10.1002/cbic.202000554

Ganley, J. G., Pandey, A., Sylvester, K., Lu, K. Y., Toro-Moreno, M., Rütschlin, S., Bradford, J. M., Champion, C. J., Böttcher, T., Xu, J., & Derbyshire, E. R. (2020). A Systematic Analysis of Mosquito-Microbiome Biosynthetic Gene Clusters Reveals Antimalarial Siderophores that Reduce Mosquito Reproduction Capacity. Cell Chemical Biology, 27(7), 817-826.e5. https://doi.org/10.1016/j.chembiol.2020.06.004


Dow, L., Stock, F., Peltekis, A., Szamosvári, D., Prothiwa, M., Lapointe, A., Böttcher, T., Bailleul, B., Vyverman, W., Kroth, P. G., & Lepetit, B. (2020). The Multifaceted Inhibitory Effects of an Alkylquinolone on the Diatom Phaeodactylum tricornutum. ChemBioChem, 21(8), 1206-1216. https://doi.org/10.1002/cbic.201900612

Pawar, A., Basler, M., Goebel, H., Alvarez Salinas, G. O., Groettrup, M., & Böttcher, T. (2020). Competitive Metabolite Profiling of Natural Products Reveals Subunit Specific Inhibitors of the 20S Proteasome. ACS Central Science, 6(2), 241-246. https://doi.org/10.1021/acscentsci.9b01170

Rütschlin, S., & Böttcher, T. (2020). Inhibitors of Bacterial Swarming Behavior. Chemistry - A European Journal, 26(5), 964-979. https://doi.org/10.1002/chem.201901961

Prothiwa, M., & Böttcher, T. (2020). Competitive profiling for enzyme inhibitors using chemical probes. In A. K. Shukla (Ed.), Chemical and Synthetic Biology Approaches To Understand Cellular Functions - Part C (pp. 49-69). ACADEMIC PRESS INC ELSEVIER SCIENCE. https://doi.org/10.1016/bs.mie.2019.10.031

Rütschlin, S., & Böttcher, T. (2020). Engineering siderophores. In A. K. Shukla (Ed.), Chemical and Synthetic Biology Approaches To Understand Cellular Functions - Part C (pp. 29-47). ACADEMIC PRESS INC ELSEVIER SCIENCE. https://doi.org/10.1016/bs.mie.2019.10.030

Durak, G. M., Laumann, M., Wolf, S. L. P., Pawar, A., Gebauer, D., & Böttcher, T. (2019). Pseudo-Biomineralization: Complex Mineral Structures Shaped by Microbes. ACS Biomaterials Science and Engineering, 5(10), 5088-5096. https://doi.org/10.1021/acsbiomaterials.9b00387





de Souza-Fagundes, E. M., Delp, J., Prazeres, P. H. D. M., Marques, L. B., Carmo, A. M. L., Stroppa, P. H. F., Glanzmann, N., Kisitu, J., Szamosvàri, D., Böttcher, T., Leist, M., & da Silva, A. D. (2018). Correlation of structural features of novel 1,2,3-triazoles with their neurotoxic and tumoricidal properties. Chemico-Biological Interactions, 291, 253-263. https://doi.org/10.1016/j.cbi.2018.06.029






21 - 40 out of 47

Microbiome-induced pruritus in atopic dermatitis patients

Wittlinger, J.-P. (Speaker), Grey, L. (Contributor), Fischer, M. (Contributor), Stary, G. (Contributor), Böttcher, T. (Contributor) & Berry, D. (Contributor)

16 Sept 2025

Activity: Talks and presentationsTalk or oral contributionScience to Science


Targeting Neisseria gonorrhoea via its toxin-antitoxin system

Böttcher, T. (Invited speaker)

20 May 2025

Activity: Talks and presentationsTalk or oral contributionScience to Science


Phage blocker: Discovery of a novel bacteriophage antiviral for phageome modulation

Plöchl, K. (Speaker) & Böttcher, T. (Contributor)

19 Feb 2025

Activity: Talks and presentationsTalk or oral contributionScience to Science


Expecting the Unexpected in the Chemistry of Microbial Interactions

Böttcher, T. (Invited speaker)

3 Oct 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Identification and Investigation of Aerugine as Trigger of Dopaminergic Neurodegeneration

Wörz, N. C. (Speaker), Ückert, A. K. (Contributor), Rütschlin , S. (Contributor), Miah, M. R. (Contributor), Martins, A. C. (Contributor), Hauer, I. (Contributor), Holzer, A. K. (Contributor), Meyburg, B. (Contributor), Mix, A.-K. (Contributor), Anderl, F. (Contributor), Hauck, C. R. (Contributor), Aschner, M. (Contributor), Leist, M. (Contributor) & Böttcher, T. (Contributor)

12 Sept 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Exploiting, and Manipulating the Secondary Metabolite Repertoire of Human Pathogens

Böttcher, T. (Invited speaker)

21 Aug 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Exploring and Exploiting the Biochemistry of Microbial Interactions

Böttcher, T. (Invited speaker)

3 May 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Microbial Metabolites Mediating Interactions in the Environment

Böttcher, T. (Invited speaker)

26 Apr 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


A Modular ABPP Approach to Target Protease AgrB in the Pathogen S. aureus

Jost, E. (Speaker) & Böttcher, T. (Contributor)

13 Mar 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Identification and investigation of aerugine as trigger of dopaminergic neurodegeneration

Wörz, N. C. (Speaker), Ückert, A. K. (Contributor), Rütschlin , S. (Contributor), Gutbier, S. (Contributor), Miah, M. R. (Contributor), Martins, A. C. (Contributor), Hauer, I. (Contributor), Holzer, A. K. (Contributor), Meyburg, B. (Contributor), Mix, A.-K. (Contributor), Anderl, F. (Contributor), Hauck, C. R. (Contributor), Aschner, M. (Contributor), Leist, M. (Contributor) & Böttcher, T. (Contributor)

13 Mar 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Chemical Biology of Virus-Microbe-Host Interactions

Böttcher, T. (Invited speaker)

14 Feb 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


A Chemist’s Approach Towards Microbe-Host Interactions

Böttcher, T. (Invited speaker)

9 Nov 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Exploiting Microbial Metabolites as Narrow- Spectrum Antibiotics

Böttcher, T. (Speaker)

11 Oct 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Small molecules in a microbial theatre

Böttcher, T. (Invited speaker)

6 Jun 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Exploring and Exploiting the Chemistry of Microbial Interactions

Böttcher, T. (Invited speaker)

31 May 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Biosynthetic Flexibility of Pseudomonas aeruginosa Leads to Hydroxylated 2-Alkylquinolones with Proinflammatory Host Response

Savchenko, V. (Speaker), Szamosvari, D. (Contributor), Bao, Y. (Contributor), Pignitter, M. (Contributor) & Böttcher, T. (Contributor)

22 Mar 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Chemical tools for modulating protein degradation

Böttcher, T. (Invited speaker)

12 Feb 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Exploring and Exploiting the Chemistry of Microbial Interactions

Böttcher, T. (Invited speaker)

26 Jan 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Small Molecules Controlling Microbial Interactions

Böttcher, T. (Invited speaker)

3 Nov 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Small Molecules Controlling Microbial Interactions

Böttcher, T. (Invited speaker)

29 Sept 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


The Chemistry of Microbial Interactions

Böttcher, T. (Invited speaker)

13 Jun 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


From Molecules to Life – a Question of Molecular Complexity

Böttcher, T. (Invited speaker)

5 Oct 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Activity-Based Probes as Chemical Tools for Targeting Proteases

Böttcher, T. (Invited speaker)

13 Jul 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Microbial metabolites for metal scavenging, defense, and signaling

Böttcher, T. (Invited speaker)

24 Jun 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Small molecules controlling prophage induction

Jancheva, M. (Speaker) & Böttcher, T. (Contributor)

18 Mar 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


A chemical tool kit for the discovery of customized enzyme inhibitors

Böttcher, T. (Invited speaker)

8 Mar 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Chemical tools for targeting the proteases of SARS-CoV-2

Böttcher, T. (Invited speaker)

28 Jan 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


A Device for Phage Capture and Release (PhageTRAP)

Böttcher, T. (Project Lead)

1/04/2630/09/27

Project: Research funding


Chemical tools for targeting bacterial effector proteins

Böttcher, T. (Project Lead)

1/04/2631/03/30

Project: Research funding


Anti-Infectives Drug Discovery

Rollinger, J. M. (Project Lead), Dailey, L. A. (Co-Lead), Orts, J. (Co-Lead), Böttcher, T. (Co-Lead), Schmidt, M. (Co-Lead), Rademacher, C. J. H. (Co-Lead), Schützenmeister, N. (Co-Lead), Zotchev, S. (Co-Lead), Kirchmair, J. (Co-Lead) & Ortmayr, K. (Co-Lead)

1/07/2531/01/30

Project: Research funding


Microbiom-induced pruritus

Berry, D. (Project Lead) & Böttcher, T. (Co-Lead)

15/02/2314/02/27

Project: Research funding



Department of Biological Chemistry

Deputy Head

Währinger Straße 38
1090 Wien

T: +43-1-4277-70550

thomas.boettcher@univie.ac.at