Univ.-Prof. Dipl.-Chem. Dr. Lothar Brecker, Privatdoz.
Lothar Brecker
T: +43-1-4277-52131
M: +43-664-8175949
Summer term 2024
270012 PR Elective Laboratory Course for Bachelor Module - Organic/Bioanorganic/Biological/Biophysical Chemistry
270115 VO Structure-determination 1D/2D NMR - Structure-determination using one- and two-diimensional NMR-Spectroscopy
270130 PR Practical Course Spectroscopy - UV/VIS, IR/Ra, NMR
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Pfeiffer, M., Crean, R. M., Moreira, C., Parracino, A., Oberdorfer, G., Brecker, L., Hammerschmidt, F., Kamerlin, S. C. L., & Nidetzky, B. (2022). Essential Functional Interplay of the Catalytic Groups in Acid Phosphatase. ACS Catalysis, 12(6), 3357-3370. https://doi.org/10.1021/acscatal.1c05656







Wongthet, N., Sanevas, N., Schinnerl, J., Brecker, L., Santimaleeworagun, W., Rosenau, T., Bacher, M., & Vajrodaya, S. (2021). Chemical constituents of Clausena lenis. Natural Product Research, 35(21), 3873–3879. https://doi.org/10.1080/14786419.2020.1747455

Wexler, A. D., Woisetschlaeger, J., Reiter, U., Reiter, G., Fuchsjaeger, M., Fuchs, E. C., & Brecker, L. (2020). Nuclear Magnetic Relaxation Mapping of Spin Relaxation in Electrically Stressed Glycerol. ACS Omega, 5(35), 22057-22070. https://doi.org/10.1021/acsomega.0c02059

1 - 20 out of 144

Investigation of biological activities of synthetic vincamine derivatives

Christina Rodler (Speaker) & Lothar Brecker (Contributor)

24 Sep 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Basics of NMR-Spectroscopy - Theory

Lothar Brecker (Invited speaker)

8 Sep 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Basics of Structure Elucidation by 1D and 2D NMR Spectroscopy

Lothar Brecker (Invited speaker)

8 Sep 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Relaxation and Nuclear Overhauser Effect

Lothar Brecker (Invited speaker)

8 Sep 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Complexation between aconitine and various flavonoids as possible concept for detoxification: A spectroscopic view on the complex formation

Lothar Brecker (Invited speaker), Christoph Itzenthaler (Contributor), Milica Grubac (Contributor) & Johann Schinnerl (Contributor)

27 May 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Yellow Twig (Nauclea orientalis): In situ 1H NMR to study strictosamide deglucosylation as a key step in alkaloid biosynthesis

Lothar Brecker (Speaker), Weerasak Songoen (Contributor), Florian Traxler (Contributor) & Johann Schinnerl (Contributor)

19 May 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Synthesis of vincamine derivatives via Pictet-Spengler reaction and investigation of their biological activities

Christina Rodler (Speaker) & Lothar Brecker (Contributor)

13 Mar 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


‘Ordinary’ 31P NMR to Study the Stereochemical Course of an ecAGP Cataylzed Phosphoryl Transfer

Lothar Brecker (Keynote speaker), Martin Pfeiffer (Contributor), Friedrich Hammerschmidt (Contributor) & Bernd Nidetzky (Contributor)

13 Sep 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


‘Ordinary’ 31P NMR to study the stereochemical course of an ecAGP cataylzed phosphoryl transfer

Lothar Brecker (Speaker), Martin Pfeiffer (Contributor), Friedrich Hammerschmidt (Contributor) & Bernd Nidetzky (Contributor)

2 Apr 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Basics of NMR-Spectroscopy

Lothar Brecker (Invited speaker)

20 Sep 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Relaxation and Nuclear Overhauser Effect

Lothar Brecker (Invited speaker)

20 Sep 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Spin−Lattice (T1) and Spin−Spin (T2) NMR Relaxation in Electrically Stressed Glycerol

Lothar Brecker (Speaker), Adam D. Wexler (Contributor), Jakob Woisetschläger (Contributor), Ursula Reiter (Contributor), Gert Reiter (Contributor), Michael Fuchsjäger (Contributor) & Elmar C. Fuchs (Contributor)

20 Sep 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Isonitriles as a potential new class of anti-malarial drugs? - Synthesis of natural product-derived isonitriles and binding studies

Evelyn Fülöp (Speaker) & Lothar Brecker (Contributor)

19 Sep 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Spin−Lattice (T1) and Spin−Spin (T2) NMR Relaxation in Electrically Stressed Glycerol

Lothar Brecker (Speaker), Adam D. Wexler (Contributor), Jakob Woisetschläger (Contributor), Ursula Reiter (Contributor), Gert Reiter (Contributor), Michael Fuchsjäger (Contributor) & Elmar C. Fuchs (Speaker)

24 Apr 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Basics of NMR-Spectroscopy

Lothar Brecker (Invited speaker)

6 Sep 2020

Activity: Talks and presentationsTalk or oral contributionScience to Science


Relaxation and Nuclear Overhauser Effect

Lothar Brecker (Invited speaker)

6 Sep 2020

Activity: Talks and presentationsTalk or oral contributionScience to Science


Paul Kosma and NMR spectroscopy - A success story that has not yet been enough appreciated

Lothar Brecker (Invited speaker)

27 Sep 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Pictet-Spengler Reactions in the Spotlight - An in situ NMR investigation

Nicole Sudzukovic (Speaker) & Lothar Brecker (Contributor)

26 Sep 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Interpretation of 1D- and 2D-NMR Spectra

Lothar Brecker (Speaker)

9 Sep 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Interpretation of 1D- and 2D-NMR Spectra (Part 3)

Lothar Brecker (Speaker)

9 Sep 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Relaxation and Nuclear Overhauser Effect

Lothar Brecker (Invited speaker)

9 Sep 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Tutorial "Basics of NMR-Spectroscopy - Part 1"

Lothar Brecker (Speaker)

9 Sep 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Tutorial "Basics of NMR-Spectroscopy - Part 2"

Lothar Brecker (Speaker)

9 Sep 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Using NMR Spectroscopy as a Sole Method for Analysis?

Lothar Brecker (Invited speaker)

25 Sep 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


New insights into the phytochemical differentiation within Psychotrieae and Palicoureeae (Rubiaceae).

Andreas Berger (Speaker), Lothar Brecker (Contributor), Johann Schinnerl (Contributor) & Karin Vetschera (Contributor)

11 Sep 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


NMR to study cascade reactions – State of the art and forecast.

Lothar Brecker (Invited speaker)

23 Apr 2017

Activity: Talks and presentationsTalk or oral contributionOther


Grundlagen der NMR-Spektroskopie

Lothar Brecker (Speaker)

12 Sep 2016

Activity: Talks and presentationsTalk or oral contributionOther


Relaxation und Nuklear Overhauser Effekt

Lothar Brecker (Speaker)

12 Sep 2016

Activity: Talks and presentationsTalk or oral contributionOther


A "red thread" through the green world of the genus Psychotria L.

Lothar Brecker (Speaker)

24 Apr 2016

Activity: Talks and presentationsTalk or oral contributionOther


Can we use alcohols to mimic water on molecular level? An NMR spectroscopic approach.

Lothar Brecker (Speaker)

19 Apr 2016

Activity: Talks and presentationsTalk or oral contributionOther


Natural products as active agents: On the border between sustainable application and risky use.

Lothar Brecker (Invited speaker)

15 Sep 2015

Activity: Talks and presentationsTalk or oral contributionOther


Are Regional Features a Key to Globalize Sustainability in Chemistry?

Lothar Brecker (Keynote speaker)

14 Sep 2015

Activity: Talks and presentationsTalk or oral contributionOther


NMR Spectroscopy as sole method? - A concerted analysis in the fight against tooth loss.

Lothar Brecker (Speaker)

19 Apr 2015

Activity: Talks and presentationsTalk or oral contributionOther


Allein nur NMR-Spektroskopie!? – Eine konzertierte Analyse im Kampf gegen Zahnausfall.

Lothar Brecker (Speaker)

12 Jan 2015

Activity: Talks and presentationsTalk or oral contributionOther


Relaxation und Nuklear Overhauser Effekt.

Lothar Brecker (Speaker)

17 Sep 2014

Activity: Talks and presentationsTalk or oral contributionOther


Grundlagen der NMR-Spektroskopie.

Lothar Brecker (Speaker)

15 Sep 2014

Activity: Talks and presentationsTalk or oral contributionOther


Green Chemistry and sustainability in education.

Lothar Brecker (Keynote speaker)

25 Aug 2014

Activity: Talks and presentationsTalk or oral contributionOther


In situ NMR and STD NMR to study mechanisms of enzyme catalyzed reactions to optimize use of enzymes in organic synthesis.

Lothar Brecker (Invited speaker)

25 Aug 2014

Activity: Talks and presentationsTalk or oral contributionOther


NMR in natural product chemistry – Studying structures and interactions

Lothar Brecker (Invited speaker)

22 May 2014

Activity: Talks and presentationsTalk or oral contributionOther


Using NMR spectroscopy to find a ‘Lost’ toxic compound in an unexpected molecular complex.

Lothar Brecker (Speaker)

27 Apr 2014

Activity: Talks and presentationsTalk or oral contributionOther


Automated signal detection for evaluation of magnetic field homogeneity from fourier transformed 1H NMR spectra.

Lothar Brecker (Speaker)

13 Jan 2014

Activity: Talks and presentationsTalk or oral contributionOther


NMR Spectroscopy of natural products!?

Lothar Brecker (Invited speaker)

19 Sep 2013

Activity: Talks and presentationsTalk or oral contributionOther


NMR of Novel Natural Products from the Genus Psychotria L. (Rubiaceae).

Lothar Brecker (Speaker)

21 Apr 2013

Activity: Talks and presentationsTalk or oral contributionOther


STD NMR and in situ NMR to study mechanisms of enzyme catalyzed reactions

Lothar Brecker (Keynote speaker)

27 Feb 2013

Activity: Talks and presentationsTalk or oral contributionOther


STD NMR und in situ NMR zur Untersuchung von Enzym-mechanismen

Lothar Brecker (Invited speaker)

Jan 2013

Activity: Talks and presentationsTalk or oral contributionOther


Grundlagen der NMR-Spektroskopie.

Lothar Brecker (Speaker)

9 Sep 2012

Activity: Talks and presentationsTalk or oral contributionOther


Relaxation und Nuklear Overhauser Effekt.

Lothar Brecker (Speaker)

9 Sep 2012

Activity: Talks and presentationsTalk or oral contributionOther


Automated signal detection for evaluation of magnetic field homogeneity from Fourier transformed 1H NMR spectra.

Lothar Brecker (Speaker)

22 Apr 2012

Activity: Talks and presentationsTalk or oral contributionOther


NMR-spectroscopy to study biocatalyzed reactions - From analysis to synthetic applications

Lothar Brecker (Invited speaker)

3 Apr 2012

Activity: Talks and presentationsTalk or oral contributionOther


NMR-spectroscopy to study biocatalyzed reactions - From analysis to synthetic applications

Lothar Brecker (Invited speaker)

30 Mar 2012

Activity: Talks and presentationsTalk or oral contributionOther


NMR-spectroscopy to study biocatalyzed reactions - From analysis to synthetic applications

Lothar Brecker (Invited speaker)

29 Mar 2012

Activity: Talks and presentationsTalk or oral contributionOther


NMR-spectroscopy to study biocatalyzed reactions - From analysis to synthetic applications

Lothar Brecker (Invited speaker)

26 Mar 2012

Activity: Talks and presentationsTalk or oral contributionOther


NMR Spektroskopie von Naturstoffen!?

Lothar Brecker (Speaker)

16 Jan 2012

Activity: Talks and presentationsTalk or oral contributionOther


Water as Solvent in Proton NMR Measurements - A Necessary Evil or a helpful Tool?

Lothar Brecker (Speaker)

16 Sep 2011

Activity: Talks and presentationsTalk or oral contributionOther


NMR of natural products Not only a tool to determine molecular structures.

Lothar Brecker (Speaker)

1 May 2011

Activity: Talks and presentationsTalk or oral contributionOther


STD-NMR in der Biokatalyse - Untersuchung nichtkovalenter Enzym-Substrat Bindungen

Lothar Brecker (Speaker)

17 Jan 2011

Activity: Talks and presentationsTalk or oral contributionOther


NMR Spectroscopy - A valuable tool to study structure and dynamics on molecular scale.

Lothar Brecker (Speaker)

5 Nov 2010

Activity: Talks and presentationsTalk or oral contributionOther


NMR Spectroscopy - A valuable tool to study structure and dynamics on molecular scale.

Lothar Brecker (Speaker)

25 Oct 2010

Activity: Talks and presentationsTalk or oral contributionOther


Grundlagen der NMR-Spektroskopie.

Lothar Brecker (Speaker)

12 Oct 2010

Activity: Talks and presentationsTalk or oral contributionOther


Relaxation und Nuklear Overhauser Effekt.

Lothar Brecker (Speaker)

12 Oct 2010

Activity: Talks and presentationsTalk or oral contributionOther


Studying biocatalyzed reactions by saturation transfer difference NMR

Lothar Brecker (Speaker)

28 May 2010

Activity: Talks and presentationsTalk or oral contributionOther


Automated signal detection and integral determination - A new approach to analyze (not only) in situ 1H NMR measurements.

Lothar Brecker (Speaker)

25 Apr 2010

Activity: Talks and presentationsTalk or oral contributionOther


NMR Based Structure Determination of Alkaloids Isolated from Plants of the Genus Psychotria L. (Rubiaceae).

Lothar Brecker (Contributor)

25 Apr 2010

Activity: Talks and presentationsTalk or oral contributionOther


STD NMR of Ternary Enzyme-Coenzyme-Substrate Complexes Binding Studies of NADH and NADPH to Candida tenuis Xylose Reductas.

Lothar Brecker (Contributor)

25 Apr 2010

Activity: Talks and presentationsTalk or oral contributionOther


Structure of fucosylated oligomannosidic N-glycans in mushrooms.

Lothar Brecker (Contributor)

11 Feb 2010

Activity: Talks and presentationsTalk or oral contributionOther


NMR Studies of xylose reductase catalyzed transformations

Lothar Brecker (Contributor)

26 Apr 2009

Activity: Talks and presentationsTalk or oral contributionOther


1H NMR Spectroscopy as tool to follow changes in the fatty acids of fish oils.

Lothar Brecker (Speaker)

26 Apr 2009

Activity: Talks and presentationsTalk or oral contributionOther


STD-NMR to Study Non-Covalent Enzyme-Carbohydrate Interactions.

Lothar Brecker (Speaker)

19 Feb 2009

Activity: Talks and presentationsTalk or oral contributionOther


Einsatz NMR-spektroskopischer Methoden zur Untersuchung biokatalysierter Reaktionen.

Lothar Brecker (Invited speaker)

27 Nov 2008

Activity: Talks and presentationsTalk or oral contributionOther


Einsatz NMR-spektroskopischer Methoden zur Untersuchung biokatalysierter Reaktionen.

Lothar Brecker (Invited speaker)

10 Jul 2008

Activity: Talks and presentationsTalk or oral contributionOther


STD NMR to study influences of co-substrates, co-enzymes, and enzyme modifications on substrate binding to biocatalysts.

Lothar Brecker (Invited speaker)

20 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


STD NMR in Biocatalysis: Study of noncovalent enzyme-carbohydrate bindings.

Lothar Brecker (Speaker)

2 Sep 2007

Activity: Talks and presentationsTalk or oral contributionOther


New Insight into an old problem - In situ NMR of acetyl group migration in glucosyl acetate / acetyl glucose.

Lothar Brecker (Speaker)

15 Apr 2007

Activity: Talks and presentationsTalk or oral contributionOther


Unusual Reaction of Ferrocenyl Nitrene Constrained within alpha-Cyclodextrin

Lothar Brecker (Contributor)

18 Sep 2006

Activity: Talks and presentationsTalk or oral contributionOther


Recent results using saturation transfer difference NMR to characterize enzyme-substrate binding.

Lothar Brecker (Speaker)

23 Apr 2006

Activity: Talks and presentationsTalk or oral contributionOther


Saturation Transfer Difference (STD) NMR to characterise binding of substrates, intermediates, and products to biocatalysts.

Lothar Brecker (Speaker)

19 Sep 2005

Activity: Talks and presentationsTalk or oral contributionOther


NMR Spectroscopic tools to identify transition states of substrates in chemical and biocatalysed reactions.

Lothar Brecker (Speaker)

4 Apr 2005

Activity: Talks and presentationsTalk or oral contributionOther


Structures of galactan and arabinogalactan polysaccharides from pollen of timothy grass (Phleum pratense L.)

Lothar Brecker (Speaker)

17 Feb 2005

Activity: Talks and presentationsTalk or oral contributionOther


Structures of galactan and arabinogalactan polysaccharides from pollen of timothy grass (Phleum pratense L.)

Lothar Brecker (Speaker)

19 Apr 2004

Activity: Talks and presentationsTalk or oral contributionOther


In situ proton NMR analysis of a-alkynoate biotransformations: From 'invisible' substrates to detectable metabolites

Lothar Brecker (Speaker)

5 Jul 2003

Activity: Talks and presentationsTalk or oral contributionOther


Recent NMR-based results from structure determination of LPS and lipid A.

Lothar Brecker (Speaker)

28 Apr 2003

Activity: Talks and presentationsTalk or oral contributionOther


Enzymic and bacterial culture biotransformations monitored by in situ proton NMR

Lothar Brecker (Invited speaker)

3 Oct 2002

Activity: Talks and presentationsTalk or oral contributionOther



Department of Organic Chemistry

Deputy Head

Währinger Straße 38
1090 Wien
Room: 1149

T: +43-1-4277-52131
M: +43-664-8175949

lothar.brecker@univie.ac.at