Assoz. Prof. Mag. Dr. Christian Kowol
Christian Kowol
Summer term 2024
270012 PR Elective Laboratory Course for Bachelor Module - Organic/Bioanorganic/Biological/Biophysical Chemistry
Summer term 2023
270012 PR Elective Laboratory Course for Bachelor Module - Organic/Bioanorganic/Biological/Biophysical Chemistry
61 - 80 out of 124

Mayr, J., Hager, S., Koblmueller, B., Klose, M. H. M., Holste, K., Fischer, B., Pelivan, K., Berger, W., Heffeter, P., Kowol, C. R., & Keppler, B. K. (2017). EGFR-targeting peptide-coupled platinum(IV) complexes. Journal of Biological Inorganic Chemistry, 22(4), 591-603. https://doi.org/10.1007/s00775-017-1450-7


Frensemeier, L., Köllensperger, G., Kowol, C., Keppler, B., & Karst, U. (2017). Electrochemistry coupled to LC/MS for the investigation of reductive and oxidative metabolic reactions of drug substances. Paper presented at 4th International Workshop on Electrochemistry/Mass Spectrometry, Münster, Germany.

Frensemeier, L., Köllensperger, G., Kowol, C., Keppler, B., & Karst, U. (2017). Electrochemical conversion of Pt(IV) prodrugs to Pt(II) cytostatics investigated by means of liquid chromatography and mass spectrometry. Paper presented at Jahrestagung der Deutschen Gesellschaft für Massenspektrometrie (DGMS) 2017, Kiel, Germany.


Frensemeier, L., Köllensperger, G., Kowol, C., Keppler, B., & Karst, U. (2017). HPLC-MS Untersuchungen zur elektrochemischen Freisetzung von Pt(II) Zytostatika aus Pt(IV)-Prodrugs. Paper presented at 27. Doktorandenseminar des AK Separation Science, Hohenroda, Germany.

Miklos, W., Heffeter, P., Pirker, C., Hager, S., Kowol, C. R., van Schoonhoven, S., Stojanovic, M., Keppler, B. K., & Berger, W. (2016). Loss of phosphodiesterase 4D mediates acquired triapine resistance via Epac-Rap1-Integrin signaling. Onco Target, 7(51), 84556-84574. https://doi.org/10.18632/oncotarget.11821

Karnthaler-Benbakka, C., Groza, D., Koblmueller, B., Terenzi, A., Holste, K., Haider, M., Baier, D., Berger, W., Heffeter, P., Kowol, C. R., & Keppler, B. K. (2016). Targeting a Targeted Drug: An Approach Toward Hypoxia-Activatable Tyrosine Kinase Inhibitor Prodrugs. ChemMedChem: chemistry enabling drug discovery, 11(21), 2410-2421. https://doi.org/10.1002/cmdc.201600417





Montano, L. G., Schwaiger, M., Theiner, S., Bamonti, L., Hermann, G., Heffeter, P., Kowol, C., Berger, W., Keppler, B., & Köllensperger, G. (2016). Mass Spectrometric Assays in Preclinical Studies on Metallodrugs. In R. Barnes (Ed.), Book of Abstracts





Berger, W., Heffeter, P., Keppler, B., & Kowol, C. (2015). NEW AGENTS FOR THE TREATMENT OF CANCER. (Patent No. WO2015144759A1).


61 - 80 out of 124

Subcellular imaging of a dual stable isotope-labeled platinum(IV) complex in murine tumor

Anton Legin (Speaker), Christian Kowol (Contributor), Arno Schintlmeister (Contributor), Hemma Schueffl (Contributor), Walter Berger (Contributor), Petra Heffeter (Contributor) & Bernhard Keppler (Contributor)

16 Oct 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Evaluation of two albumin-targeting moieties as in situ binders in comparison to maleimide

Anja Federa (Speaker), H. Schueffl (Contributor), Alexander Kastner (Contributor), Julia Kronberger (Contributor), Bernhard Keppler (Contributor), Thomas Mindt (Contributor), P. Heffeter (Contributor) & Christian Kowol (Contributor)

3 Sep 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Elemental analysis: Essential purity control but prone to manipulations

Wolfgang Kandioller (Contributor), Johannes Theiner (Contributor), Bernhard Keppler (Contributor) & Christian Kowol (Invited speaker)

11 Jun 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Impact of albumin-targeting on the anticancer activity and tumor distribution of platinum(IV) prodrugs

Hemma Schueffl (Contributor), Sarah Theiner (Contributor), Oliver Baumfried (Contributor), Gunda Köllensperger (Contributor), Anton Legin (Contributor), Bernhard Keppler (Contributor), Walter Berger (Contributor), Christian Kowol (Invited speaker) & Petra Heffeter (Speaker)

11 Jun 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Anticancer drug development: a chemist´s view

Christian Kowol (Invited speaker)

17 Nov 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Impact of albumin-targeting on the pharmacology, tissue distribution and anticancer activity of an oxaliplatin(IV) bismaleimide prodrug in vivo

Hemma Schueffl (Speaker), Sarah Theiner (Contributor), Gunda Köllensperger (Contributor), Bernhard Keppler (Contributor), Walter Berger (Contributor), Christian Kowol (Contributor), Anton Legin (Contributor) & Petra Heffeter (Speaker)

29 Jun 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Crucial Parameters for Platinum(IV) Anticancer Drug development

Christian Kowol (Invited speaker)

13 Jun 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Hydrolysis of equatorial ligands of platinum(IV) complexes

Alexander Kastner (Keynote speaker), Isabella Pötsch (Contributor), Petra Heffeter (Contributor), Bernhard Keppler (Contributor) & Christian Kowol (Contributor)

24 Sep 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Crucial parameters for platinum(IV) anticancer drug development

Christian Kowol (Keynote speaker)

30 Jun 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Aquation of equatorial ligands of Pt(IV) complexes under physiological conditions

Christian Kowol (Keynote speaker)

11 Jun 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Albumin-targeted platinum(IV) complexes with outstanding antitumor activity in vivo

Christian Kowol (Speaker)

26 Aug 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Prodrugs and Tumor-specific Activation

Christian Kowol (Invited speaker)

24 Jun 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Distinctly enhanced anticancer activity in vivo by albumin-targeted platinum(IV) prodrugs

Christian Kowol (Invited speaker)

14 Aug 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


Metallomics and metabolomics studies in preclinical anticancer research of oxaliplatin

Luis Galvez (Speaker), Michaela Schwaiger (Contributor), Sonja Hager (Contributor), Christian Kowol (Contributor), Petra Heffeter (Contributor), Walter Berger (Contributor) & Gunda Köllensperger (Contributor)

14 Aug 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


Albumin-based tumor-targeted platinum(IV) prodrugs with distinctly enhanced anticancer activity in vivo

Christian Kowol (Invited speaker)

12 Jul 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


Understanding the metabolism of the anticancer drug Triapine by application of electrochemistry and liquid chromatography coupled to mass spectrometry

Karla Pelivan (Speaker), Lisa Frensemeier (Contributor), Uwe Karst (Contributor), Gunda Köllensperger (Contributor), Björn Bielec (Contributor), Petra Heffeter (Contributor), Christian Kowol (Contributor) & Bernhard Keppler (Contributor)

12 May 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


Maleimid-functionalized Platinum(IV) complexes for tumor-Targeted Drug Delivery

Christian Kowol (Speaker)

28 Aug 2016

Activity: Talks and presentationsTalk or oral contributionOther


Tyrosine-kinase receptor targeted platinum(IV) complexes

Christian Kowol (Invited speaker)

28 Apr 2016

Activity: Talks and presentationsTalk or oral contributionOther


Prodrugs as the next step in drug development

Christian Kowol (Invited speaker)

2016

Activity: Talks and presentationsTalk or oral contributionScience to Science


Prodrug strategies for tumor-specific anticancer activity

Christian Kowol (Invited speaker)

7 Mar 2015

Activity: Talks and presentationsTalk or oral contributionOther


A COBALT-BASED PRODRUG STRATEGY FOR TUMOR-TARGETING OF EGFR-INHIBITORS

Christian Kowol (Invited speaker)

14 Dec 2014

Activity: Talks and presentationsTalk or oral contributionOther


The search for novel anticancer drugs

Christian Kowol (Invited speaker)

11 Oct 2013

Activity: Talks and presentationsTalk or oral contributionOther


Development and optimization of multifunctional nanoparticles for molecular imaging and therapy

Christian Kowol (Contributor)

28 Jun 2012

Activity: Talks and presentationsTalk or oral contributionOther



Marker für die Aktivität von Albumin-bindenden Verbindungen

Heffeter, P., Mindt, T. & Kowol, C.

1/08/2031/07/24

Project: Research funding



Nanocarrier for Tumor-Specific Anticancer Thiosemicarbazones

Kowol, C., Heffeter, P. & Teasdale, I.

1/05/1930/04/23

Project: Research funding


Prodrugs von Kinase-Inhibitoren

Kowol, C.

4/12/154/12/18

Project: Research funding


Tumor-targeting

Kowol, C.

9/12/138/12/16

Project: Research funding


Department of Inorganic Chemistry

Deputy Head

Währinger Straße 42
1090 Wien
Room: 2164

T: +43-1-4277-52611

christian.kowol@univie.ac.at