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Pashkunova-Martic, I., Klose, M. H. M., Kudela, P., Groza-Weber, D., Reipert, S., Kowol, C. R., Heffeter, P., Berger, W., Keppler, B. K., & Lubitz, W. (2026). Bacterial Ghosts as Innovative Transport Vehicles for Platinum-Based Anticancer Drugs. ChemMedChem, 21(12), Artikel e70351. https://doi.org/10.1002/cmdc.70351

Kronberger, J., Neuzilova, B., Federa, A., Tieber, M., Palombo, A., Brandt, M. R., Heffeter, P., Kowol, C. R., Petrik, M., & Mindt, T. L. (2026). Side-by-Side Comparison of Different Thiol Bioconjugation Strategies for the Chemoselective Radiolabeling of Human Serum Albumin with Zirconium-89. ACS bio & med chem Au : an open access journal of the American Chemical Society , 6(3), 282-292. https://doi.org/10.1021/acsbiomedchemau.6c00002

Gutmann, M., Dijkstra, M., Salomon, P., Cowles, J., Federa, A., Baier, D., Jaunecker, C., Semerean, I., Karvonen, V., Pirker, C., Sibilia, M., Herndler-Brandstetter, D., Heffeter, P., Keppler, B. K., Kowol, C. R., & Berger, W. (2026). Improved Systemic Immunochemotherapy Employing an Oxaliplatin-TLR7/8 Agonist Prodrug Strategy. Advanced Science, 13(31), Artikel e14588. https://doi.org/10.1002/advs.202514588

Bormio Nunes, J. H., Hacker, C., Caban, M., Valcanover, D., Yassemipour, P. A., Türck, S., Ott, I., Skos, L., Bileck, A., Gerner, C., Meier-Menches, S. M., Mohr, T., Berger, W., Kowol, C. R., & Heffeter, P. (2026). Structure-Activity Relationships of Silver(I)- and Gold(I)-NHC Complexes Reveal Distinctly Different Responses of Cisplatin-Resistant Ovarian Cancer to Bis-NHC-Gold(I) Derivatives. Journal of Medicinal Chemistry, 69(3), 2462-2480. Artikel PMID 9716531. https://doi.org/10.1021/acs.jmedchem.5c02355

Federa, A., Pitek, R., Dömötör, O., Enyedy, É. A., Terenzi, A., Caban, M., Stefanelli, A., D’Anna, L., White, F., Heffeter, P., & Kowol, C. R. (2026). Tumor-Targeted Delivery of an EGFR Inhibitor Prodrug via Site-Specific Albumin Conjugation. Journal of Medicinal Chemistry, 69(3), 2554-2574. https://doi.org/10.1021/acs.jmedchem.5c02536

Bahjou, Y., Draoui, Y., Radi, S., Robeyns, K., Li, W., Miras, H. N., Ferbinteanu, M., Rotaru, A., Bittner, H., Jakupec, M. A., Kowol, C. R., Cvetkovic, O., Wolff, M., & Garcia, Y. (2026). Coordination Complexes and Polymers of Novel Hybrid Tetrazole-Triazole-Pyrazole Ligands: Synthesis, Structural Characterization, and Biological Evaluation. Chemistry - A European Journal. Vorzeitige Online-Publikation. https://doi.org/10.1002/chem.202502238

D'Anna, L., Froux, A., Bonsignore, R., Roller, A., Kowol, C. R., Monari, A., Grandemange, S., Barone, G., & Terenzi, A. (2026). In medio stat virtus: asymmetric Salphen metal complexes with improved biological properties. Dalton Transactions. Vorzeitige Online-Publikation. https://doi.org/10.1039/d5dt02881g

Stiller, B., Stefanelli, A., Schueffl, H., Mathuber, M., Skorokhyd, N., Gufler, J., Pirker, C., Holcmann, M., Panchuk, R., Sibilia, M., Marko, D., Berger, W., Kowol, C. R., Hager, S., & Heffeter, P. (2025). The anticancer thiosemicarbazone triapine exerts immune-enhancing activities via immunogenic cell death induction and FAS upregulation. Experimental Hematology and Oncology, 14(1), Artikel 109. https://doi.org/10.1186/s40164-025-00700-0

Vinjamuri, B., Kowol, C. R., & Faller, P. (2025). Low Catalytic Redox Activity of α-N-Pyridylthiosemicarbazone Iron Complexes Suggests an Indirect ROS Generation Mechanism in Their Biological Activity. Inorganic Chemistry, 64(40), 20340-20347. https://doi.org/10.1021/acs.inorgchem.5c03520

Federa, A., Schueffl, H., Minichmayr, I. K., Kastner, A., Kronberger, J., Mindt, T. L., Heffeter, P., & Kowol, C. R. (2025). Comparative Evaluation of Thiol- and Amine-Conjugating Moieties for Endogenous Albumin Binding after Intravenous Administration. ACS Pharmacology and Translational Science, 8(7), 2192-2203. https://doi.org/10.1021/acsptsci.5c00240

Kronberger, J., Balber, T., Schueffl, H., Wahrmann, R., Federa, A., Gradl, M., Brandt, M. R., Wanek, T., Mitterhauser, M., Kowol, C. R., Mindt, T. L., & Heffeter, P. (2025). Site-Selectively Functionalized Albumin with DFO*Maleimide for ⁸⁹Zr-Radiolabeling Yields a Metabolically Stable PET Probe that Enables Late Time-Point Tumor Imaging in Mice. Journal of Medicinal Chemistry, 68(12), 12925-12939. https://doi.org/10.1021/acs.jmedchem.5c00803

Dijkstra, M., Gutmann, M., Gradl, M., Federa, A., Jaunecker, C., Breitenstein, J. V., Vician, P., Pirker, C., Valcanover, D., Heffeter, P., Keppler, B. K., Berger, W., & Kowol, C. R. (2025). Albumin-targeted oxaliplatin(iv) prodrugs bearing STING agonists. Inorganic Chemistry Frontiers, 12(13), 4284-4305. https://doi.org/10.1039/d5qi00433k

Dijkstra, M., Schueffl, H., Federa, A., Kast, C., Unterlercher, A., Keppler, B. K., Heffeter, P., & Kowol, C. R. (2025). Novel Maleimide Linkers Based on a Piperazine Motif for Strongly Increased Aqueous Solubility. ACS Omega, 10(5), 5047-5063. https://doi.org/10.1021/acsomega.4c10825

Dijkstra, M., Schueffl, H., Adamova, B., Baumfried, O., Kastner, A., Berger, W., Keppler, B. K., Heffeter, P., & Kowol, C. R. (2025). Exploring the Structure-Activity Relationships of Albumin-Targeted Picoplatin-Based Platinum(IV) Prodrugs. Inorganic Chemistry, 64(5), 2554-2566. https://doi.org/10.1021/acs.inorgchem.4c05269

Gufler, J., Heffeter, P., Kowol, C. R., Hager, S., & Marko, D. (2025). Opposing effects of mycotoxins alternariol and deoxynivalenol on the immunomodulatory effects of oxaliplatin and triapine. Toxicology, 511, Artikel 154039. https://doi.org/10.1016/j.tox.2024.154039

Caban, M., Fronik, P., Terenzi, A., Federa, A., Bormio Nunes, J. H., Pitek, R., Kirchhofer, D., Schueffl, H. H., Berger, W., Keppler, B. K., Kowol, C. R., & Heffeter, P. (2025). A new fluorescent oxaliplatin(iv) complex with EGFR-inhibiting properties for the treatment of drug-resistant cancer cells. Inorganic Chemistry Frontiers, 12(4), 1538-1552. https://doi.org/10.1039/d4qi03025g

Stiller, B., Hager, S., Filipović, N. R., Kowol, C. R., & Heffeter, P. (Angenommen/Im Druck). Schiff bases and cancer drug resistance: key preclinical breakthroughs. Future Medicinal Chemistry. https://doi.org/10.1080/17568919.2025.2561540

Mosca, E., Federa, A., Pirker, C., Schosserer, M., Liendl, L., Eckhard, M., Sombke, A., Dömötör, O., Kirchhofer, D., Timelthaler, G., Baier, D., Gurschka, P., Gabler, L., Reithofer, M., Chin, J. M., Elsayad, K., Englinger, B., Tahir, A., Kowol, C. R., & Berger, W. (2024). The tyrosine kinase inhibitor Nintedanib induces lysosomal dysfunctionality: Role of protonation-dependent crystallization processes. Chemico-Biological Interactions, 403, Artikel 111243. https://doi.org/10.1016/j.cbi.2024.111243

Teixeira, R. G., Stefanelli, A., Pilon, A., Warmers, R., Fontrodona, X., Romero, I., Costa, P. J., Villa de Brito, M. J., Hudec, X., Pirker, C., Türck, S., Antunes, A. M. M., Kowol, C. R., Ott, I., Brozovic, A., Sombke, A., Eckhard, M., Tomaz, A. I., Heffeter, P., & Valente, A. (2024). Paraptotic Cell Death as an Unprecedented Mode of Action Observed for New Bipyridine-Silver(I) Compounds Bearing Phosphane Coligands. Journal of Medicinal Chemistry, 67(8), 6081-6098. https://doi.org/10.1021/acs.jmedchem.3c01036

Podolski-Renić, A., Čipak Gašparović, A., Valente, A., López, Ó., Bormio Nunes, J. H., Kowol, C. R., Heffeter, P., & Filipović, N. R. (2024). Schiff bases and their metal complexes to target and overcome (multidrug) resistance in cancer. European Journal of Medicinal Chemistry, 270, Artikel 116363. https://doi.org/10.1016/j.ejmech.2024.116363