Univ.-Prof. Dipl.-Phys. Dr. Ivo Hofacker
Ivo Hofacker
Summer term 2024
270020 PR Bachelor Laboratory Course D - Theoretical Chemistry and Computational Biological Chemistry
500501 SE Doctoral Research Seminar - Data and Knowledge
1 - 20 out of 185




Farman, M. R., Petrackova, D., Kumar, D., Drzmisek, J., Saha, A., Curnova, I., Capek, J., Hejnarova, V., Amman, F., Hofacker, I., & Vecerek, B. (2023). Avirulent phenotype promotes Bordetella pertussis adaptation to the intramacrophage environment. Emerging microbes & infections, 12(1), Article e2146536. https://doi.org/10.1080/22221751.2022.2146536




Mrozowich, T., Park, S. M., Waldl, M., Henrickson, A., Tersteeg, S., Nelson, C. R., De Klerk, A., Demeler, B., Hofacker, I. L., Wolfinger, M. T., & Patel, T. R. (2023). Investigating RNA-RNA interactions through computational and biophysical analysis. Nucleic Acids Research, 51(9), 4588-4601. https://doi.org/10.1093/nar/gkad223






Wolfinger, M. T., Ochsenreiter, R. W., & Hofacker, I. (2021). Functional RNA Structures in the 3′ UTR of Mosquito-Borne Flaviviruses. In D. Frishman, & M. Marz (Eds.), Virus Bioinformatics Chapman and Hall/CRC. https://doi.org/10.1201/9781003097679

Mueller, T., Miladi, M., Hutter, F., Hofacker, I., Will, S., & Backofen, R. (2020). The locality dilemma of Sankoff-like RNA alignments. Bioinformatics, 36, I242-I250. https://doi.org/10.1093/BIOINFORMATICS/BTAA431

Petrackova, D., Farman, M. R., Amman, F., Linhartova, I., Dienstbier, A., Kumar, D., Drzmisek, J., Hofacker, I., Eugenia Rodriguez, M., & Vecerek, B. (2020). Transcriptional profiling of human macrophages during infection with Bordetella pertussis. RNA Biology, 17(5), 731-742. https://doi.org/10.1080/15476286.2020.1727694

Kim, D. N., Thiel, B. C., Mrozowich, T., Hennelly, S. P., Hofacker, I. L., Patel, T. R., & Sanbonmatsu, K. Y. (2020). Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution. Nature Communications, 11(1), Article 148. https://doi.org/10.1038/s41467-019-13942-4

Waldl, M., Will, S., Wolfinger, M. T., Hofacker, I. L., & Stadler, P. F. (2020). Bi-alignments as models of incongruent evolution of RNA sequence and secondary structure. In P. Cazzaniga, D. Besozzi, I. Merelli, & L. Manzoni (Eds.), Computational Intelligence Methods for Bioinformatics and Biostatistics: 16th International Meeting, CIBB 2019, Revised Selected Papers (Vol. 12313, pp. 159-170). Springer. https://doi.org/10.1007/978-3-030-63061-4_15

Lorenz, R., Flamm, C., Hofacker, I. L., & Stadler, P. F. (2020). Efficient Computation of Base-pairing Probabilities in Multi-strand RNA Folding. In E. DeMaria, A. Fred, & H. Gamboa (Eds.), Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies: Volume 3: BIOINFORMATICS, 23-31, 2020 , Valletta, Malta (pp. 23-31). SciTePress. https://doi.org/10.5220/0008916600230031

1 - 20 out of 185

Coarse Grained Sampling of 3D RNA Structures in Ernwin

Ivo Hofacker (Speaker)

21 Jul 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Structure and Design of RNase resistant RNA structures

Leonhard Paul Sidl (Speaker) & Ivo Hofacker (Contributor)

19 Feb 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Free energy calculation of modified nucleotides by molecular dynamics simulations

Thomas Spicher (Speaker), Ronny Lorenz (Contributor) & Ivo Hofacker (Contributor)

11 Feb 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


The effect of modified nucleotides on RNA structure

Yuliia Varenyk (Speaker), Ronny Lorenz (Contributor), Thomas Spicher (Contributor) & Ivo Hofacker (Contributor)

11 Feb 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


The effect of modified nucleotides on RNA structure

Yuliia Varenyk (Speaker), Ronny Lorenz (Contributor), Thomas Spicher (Contributor) & Ivo Hofacker (Contributor)

1 Feb 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Computational Estimation of Energy Parameters

Thomas Spicher (Speaker), Ronny Lorenz (Contributor) & Ivo Hofacker (Contributor)

12 Feb 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Modeling RNA-RNA interaction formation on direct paths

Maria Waldl (Speaker), Ivo Hofacker (Contributor) & Sebastian Will (Contributor)

12 Feb 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


The effect of modified nucleotides on secondary structure prediction in tRNA

Yuliia Varenyk (Speaker), Ivo Hofacker (Contributor), Ronny Lorenz (Contributor) & Thomas Spicher (Contributor)

12 Feb 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Predicting the effect of modified nucleotides on RNA structure

Ivo Hofacker (Invited speaker)

26 Oct 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Computational Estimation of Energy Parameters for modified Nucleotides

Thomas Spicher (Speaker), Ronny Lorenz (Contributor) & Ivo Hofacker (Contributor)

3 Oct 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Incongruent Evolution of RNA Sequence and Structure

Maria Waldl (Speaker), Sebastian Will (Contributor), Michael Thomas Wolfinger (Contributor), Ivo Hofacker (Contributor) & Peter Stadler (Contributor)

3 Oct 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Modified nucleotides in RNA secondary structure prediction

Yuliia Varenyk (Speaker), Ivo Hofacker (Contributor), Ronny Lorenz (Contributor) & Thomas Spicher (Contributor)

3 Oct 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Experiments in Deep Learning for RNA Secondary Structure Prediction

Ivo Hofacker (Invited speaker)

18 Sept 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Features of RNA-RNA interaction kinetics

Maria Waldl (Speaker), Sebastian Will (Contributor) & Ivo Hofacker (Contributor)

18 Sept 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Simulations of cotranscriptional folding explain the impact of sequence mutations

Stefan Badelt (Speaker), Ronny Lorenz (Contributor) & Ivo Hofacker (Contributor)

18 Sept 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Experiments in Deep Learning for RNA Secondary Structure Prediction

Ivo Hofacker (Keynote speaker)

6 Sept 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


An RNA kinetics ansatz derived from an efficient prediction of RNA pathways

Ivo Hofacker (Invited speaker)

7 Aug 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Experiments in Deep Learning for RNA Secondary Structure Prediction

Ivo Hofacker (Invited speaker)

7 Aug 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Incongruent Evolution of RNA Sequence and Structure

Maria Waldl (Speaker), Sebastian Will (Contributor), Ivo Hofacker (Contributor) & Peter Stadler (Contributor)

7 Aug 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Modeling RNA-RNA interaction formation on direct paths

Maria Waldl (Speaker), Irene Katharina Beckmann-Schneider (Contributor), Sebastian Will (Contributor) & Ivo Hofacker (Contributor)

7 Aug 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


MODELING THE KINETICS OF RNA-RNA INTERACTION FORMATION

Maria Waldl (Speaker), Irene Katharina Beckmann-Schneider (Contributor), Sebastian Will (Contributor) & Ivo Hofacker (Contributor)

17 Nov 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Prediction of co-transcriptional RNA folding for Modeling Riboswitches

Ivo Hofacker (Keynote speaker)

7 Oct 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Bi-alignments as Models of Incongruent Evolution of RNA Sequence and Structure

Maria Waldl (Speaker), Sebastian Will (Contributor), Michael Thomas Wolfinger (Contributor), Ivo Hofacker (Contributor) & Peter Stadler (Contributor)

30 Sept 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Co-transcriptional RNA folding kinetics

Ivo Hofacker (Invited speaker)

9 Sept 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Bi-alignments as Models of Incongruent Evolution of RNA Sequence and Structure

Maria Waldl (Contributor), Sebastian Will (Contributor), Michael Thomas Wolfinger (Contributor), Ivo Hofacker (Speaker) & Peter Stadler (Contributor)

4 Sept 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Human & Bordetella pertussis co-expression networks

Mariam Rukhama Farman (Speaker) & Ivo Hofacker (Contributor)

10 Feb 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Computational Approaches to RNA Folding Kinetics

Ivo Hofacker (Invited speaker)

15 Jan 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


RNA secondary Structures

Ivo Hofacker (Invited speaker)

14 Jan 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


RNA-RNA Interaction Kinetics for Refining RNA Targeting Screens

Maria Waldl (Speaker), Sebastian Will (Contributor) & Ivo Hofacker (Contributor)

1 Oct 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


RNA-RNA Interaction Kinetics for Refining RNA Targeting Screens

Maria Waldl (Speaker), Sebastian Will (Contributor) & Ivo Hofacker (Contributor)

25 Sept 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Co-transcriptional Folding Kinetics and Riboswitch Modeling

Ivo Hofacker (Invited speaker)

15 Jul 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Identification and Classification of Pseudoknots and their Impact on RNA 3D structure prediction

Irene Katharina Beckmann-Schneider (Speaker), Bernhard Thiel (Contributor) & Ivo Hofacker (Contributor)

11 Feb 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Predicting Pseudoknots in RNA 3D structures

Irene Katharina Beckmann-Schneider (Speaker) & Ivo Hofacker (Contributor)

2 Oct 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


RNA 2D folding Dynamics and 3D Structure Prediction

Ivo Hofacker (Invited speaker)

26 May 2016

Activity: Talks and presentationsTalk or oral contributionOther


Coarse Grain 3D RNA Structure Prediction

Ivo Hofacker (Invited speaker)

14 Apr 2016

Activity: Talks and presentationsTalk or oral contributionOther


Computational Biology with RNA Structures, Interactions, and Dynamics

Ivo Hofacker (Invited speaker)

9 Jan 2016

Activity: Talks and presentationsTalk or oral contributionOther


Beyond RNA secondary structure

Ivo Hofacker (Invited speaker)

28 Jun 2014

Activity: Talks and presentationsTalk or oral contributionOther


siRNA and Oligo Design

Ivo Hofacker (Invited speaker)

25 Jun 2014

Activity: Talks and presentationsTalk or oral contributionOther


RNA folding kinetics and energy landscapes

Ivo Hofacker (Invited speaker)

24 Jun 2014

Activity: Talks and presentationsTalk or oral contributionOther


Energy directed RNA folding

Ivo Hofacker (Invited speaker)

23 Jun 2014

Activity: Talks and presentationsTalk or oral contributionOther


In silico Annotation of noncoding RNAs and their Targets

Ivo Hofacker (Invited speaker)

11 Apr 2014

Activity: Talks and presentationsTalk or oral contributionOther


Beyond RNA secondary structure:G-quadruplexes and non-canonical pairs

Ivo Hofacker (Invited speaker)

26 Jun 2013

Activity: Talks and presentationsTalk or oral contributionOther


Predicting Targets and Effects of Bacterial small RNAs

Ivo Hofacker (Invited speaker)

4 Jun 2013

Activity: Talks and presentationsTalk or oral contributionOther


Predicting functional RNA structures

Ivo Hofacker (Speaker)

11 Oct 2012

Activity: Talks and presentationsTalk or oral contributionOther


Folding with Fancy Constraints -Secondary Structures from Probing Data

Ivo Hofacker (Speaker)

24 Jul 2012

Activity: Talks and presentationsTalk or oral contributionOther


RNA Structures, Interactions, and Folding Kinetics

Ivo Hofacker (Speaker)

4 Jul 2012

Activity: Talks and presentationsTalk or oral contributionOther


Folding Kinetics and Energy Landscapes for RNA Secondary Structures

Ivo Hofacker (Speaker)

21 Jun 2012

Activity: Talks and presentationsTalk or oral contributionOther


RNA in silico: Bioinformatik im postgenomischen Zeitalter

Ivo Hofacker (Invited speaker)

9 May 2012

Activity: Talks and presentationsTalk or oral contributionOther


RNA Folding Kinetics and Dynamic Landscapes

Ivo Hofacker (Speaker)

20 Jan 2012

Activity: Talks and presentationsTalk or oral contributionOther


Advances in RNA Bioinformatics. Prediction of RNA Structures, Interactions, and Folding Kinetics

Ivo Hofacker (Speaker)

19 Nov 2011

Activity: Talks and presentationsTalk or oral contributionOther


The art of RNA homology search

Ivo Hofacker (Speaker)

15 Nov 2011

Activity: Talks and presentationsTalk or oral contributionOther


Prediction of bacterial small RNA targets

Ivo Hofacker (Speaker)

16 Jul 2011

Activity: Talks and presentationsTalk or oral contributionOther


Micro RNA Discovery in Sequencing Data without a Genome

Ivo Hofacker (Speaker)

15 Jul 2011

Activity: Talks and presentationsTalk or oral contributionOther


Beyond secondary structures: Predicting non-canonical pairs

Ivo Hofacker (Speaker)

26 May 2011

Activity: Talks and presentationsTalk or oral contributionOther


In silico annotation of noncoding RNAs and their targets

Ivo Hofacker (Speaker)

13 May 2011

Activity: Talks and presentationsTalk or oral contributionOther


RNA Folding Dynamics -- trajectories and landscapes

Ivo Hofacker (Invited speaker)

30 Apr 2010

Activity: Talks and presentationsTalk or oral contributionOther


RNA Genefinding

Ivo Hofacker (Invited speaker)

28 Apr 2010

Activity: Talks and presentationsTalk or oral contributionOther


Energy Landscapes for RNA Folding: Time- dependent Landscapes and 2D Projections

Ivo Hofacker (Invited speaker)

5 Aug 2009

Activity: Talks and presentationsTalk or oral contributionOther


Bioinformatics for the Modern RNA World:From Gene Finding to Function

Ivo Hofacker (Invited speaker)

9 Jul 2009

Activity: Talks and presentationsTalk or oral contributionOther


Detection, annotation, and target search for noncoding RNAs

Ivo Hofacker (Invited speaker)

26 Jan 2009

Activity: Talks and presentationsTalk or oral contributionOther


ncRNA Annotation and Target Prediction

Ivo Hofacker (Invited speaker)

13 Jan 2009

Activity: Talks and presentationsTalk or oral contributionOther


RNA Bioinformatics: From structure prediction to RNA gene finding

Ivo Hofacker (Invited speaker)

12 Nov 2008

Activity: Talks and presentationsTalk or oral contributionOther


Introduction to non-coding RNA gene finding

Ivo Hofacker (Invited speaker)

19 Jul 2008

Activity: Talks and presentationsTalk or oral contributionOther


From noncoding RNA Search to Annotation

Ivo Hofacker (Invited speaker)

28 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


Prediction of ncRNA Interaction Targets

Ivo Hofacker (Invited speaker)

28 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


RNA Structure thermodynamics, basic folding

Ivo Hofacker (Invited speaker)

14 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


Solving RNA bioinformatics problems using the Vienna RNA Package

Ivo Hofacker (Invited speaker)

14 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


Stochastic Models, HMMs, SCFGs, and model training

Ivo Hofacker (Invited speaker)

14 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


Computational Detection and Analysis of noncoding RNAs

Ivo Hofacker (Invited speaker)

4 Feb 2008

Activity: Talks and presentationsTalk or oral contributionOther


Prediction of RNA-RNA interaction

Ivo Hofacker (Invited speaker)

29 Oct 2007

Activity: Talks and presentationsTalk or oral contributionOther


Prediction of RNA-RNA interaction

Ivo Hofacker (Invited speaker)

20 Oct 2007

Activity: Talks and presentationsTalk or oral contributionOther


Computational Detection and Annotation of Non-Coding RNAs

Ivo Hofacker (Invited speaker)

30 Sept 2007

Activity: Talks and presentationsTalk or oral contributionOther


Basic Algorithms in RNA Bioinformatics

Ivo Hofacker (Invited speaker)

17 Sept 2007

Activity: Talks and presentationsTalk or oral contributionOther


Noncoding RNAs in Bacteria

Ivo Hofacker (Invited speaker)

17 Sept 2007

Activity: Talks and presentationsTalk or oral contributionOther


RNA Bioinformatics -- An Overview

Ivo Hofacker (Invited speaker)

17 Sept 2007

Activity: Talks and presentationsTalk or oral contributionOther


Prediction of RNA-RNA interaction

Ivo Hofacker (Invited speaker)

21 May 2007

Activity: Talks and presentationsTalk or oral contributionOther


RNAdeco: decorating RNA for a purpose

Jantsch, M. F., Ameres, S. & Hofacker, I.

1/03/2029/02/28

Project: Research funding


Vorhersage von RNA-RNA Interakt

Hofacker, I.

1/12/1630/11/20

Project: Research funding


Transcri. Analyse von Bordetell

Hofacker, I.

29/10/1528/10/18

Project: Research funding


RNA-Funktionskontrolle

Hofacker, I.

24/03/1123/03/14

Project: Research funding


nicht kodierende RNAs

Hofacker, I.

1/12/1031/01/19

Project: Research funding


RNA Biology

Leodolter-Barta, A., von Haeseler, A., Bläsi, U., Görke, B., Hofacker, I., Moll, I., Ayatollahi, Z. & Martins, A.

1/12/0630/06/21

Project: Research funding


Department of Theoretical Chemistry

Head

Währinger Straße 17
1090 Wien
Room: 306/307

T: +43-1-4277-52738

ivo.hofacker@univie.ac.at