Univ.-Prof. Dipl.-Phys. Dr. Ivo Hofacker
Ivo Hofacker
1 - 20 out of 190
Hanisch, M., Flemmich, L., Mitteregger, C., Bauer, I., Velandia-Huerto, C. A., Hofacker, I., Micura, R., & Lusser, A. (2025). Experimental identification of preQ1-binding RNAs in the pathogenic bacterium Listeria monocytogenes. RSC Chemical Biology. Advance online publication. https://doi.org/10.1039/d5cb00102a


Boury, T., Sidl, L., Hofacker, I. L., Ponty, Y., & Yao, H. T. (2025). Old Dog, New Tricks: Exact Seeding Strategy Improves RNA Design Performances. In S. Sankararaman (Ed.), Research in Computational Molecular Biology - 29th International Conference, RECOMB 2025, Proceedings (pp. 134-152). Springer Science and Business Media Deutschland GmbH. https://doi.org/10.1007/978-3-031-90252-9_9

Rappol, T., Waldl, M., Chugunova, A., Hofacker, I. L., Pauli, A., & Vilardo, E. (2024). tRNA expression and modification landscapes, and their dynamics during zebrafish embryo development. Nucleic Acids Research, 52(17), 10575-10594. https://doi.org/10.1093/nar/gkae595


Waldl, M., Yao, H. T., & Hofacker, I. L. (2024). Sequence Design for RNA-RNA Interactions. In A. Churkin, & D. Barash (Eds.), RNA Design: Methods and Protocols (pp. 1-16). Springer Nature. https://doi.org/10.1007/978-1-0716-4079-1_1

Backofen, R., Gorodkin, J., Hofacker, I., & Stadler, P. (2024). Comparative RNA Genomics. In Comparative Genomics: Methods and Protocols (2 ed., pp. 347–393). Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3838-5_12

von Löhneysen, S., Spicher, T., Varenyk, Y., Yao, H. T., Lorenz, R., Hofacker, I., & Stadler, P. F. (2024). Phylogenetic and Chemical Probing Information as Soft Constraints in RNA Secondary Structure Prediction. Journal of computational biology : a journal of computational molecular cell biology, 31(6), 549-563. https://doi.org/10.1089/cmb.2024.0519


Farman, M. R., Petrackova, D., Kumar, D., Drzmisek, J., Saha, A., Curnova, I., Capek, J., Hejnarova, V., Amman, F., Hofacker, I., & Vecerek, B. (2023). Avirulent phenotype promotes Bordetella pertussis adaptation to the intramacrophage environment. Emerging microbes & infections, 12(1), Article e2146536. https://doi.org/10.1080/22221751.2022.2146536



Waldl, M., Spicher, T., Lorenz, R., Beckmann, I. K., Hofacker, I. L., Von Löhneysen, S., & Stadler, P. F. (2023). Local RNA folding revisited. Journal of Bioinformatics and Computational Biology, 21(4), Article 2350016. https://doi.org/10.1142/S0219720023500166

Mrozowich, T., Park, S. M., Waldl, M., Henrickson, A., Tersteeg, S., Nelson, C. R., De Klerk, A., Demeler, B., Hofacker, I. L., Wolfinger, M. T., & Patel, T. R. (2023). Investigating RNA-RNA interactions through computational and biophysical analysis. Nucleic Acids Research, 51(9), 4588-4601. https://doi.org/10.1093/nar/gkad223






Wolfinger, M. T., Ochsenreiter, R. W., & Hofacker, I. (2021). Functional RNA Structures in the 3′ UTR of Mosquito-Borne Flaviviruses. In D. Frishman, & M. Marz (Eds.), Virus Bioinformatics Chapman and Hall/CRC. https://doi.org/10.1201/9781003097679

1 - 20 out of 190

Predicting the Effect of RNA Modifications on RNA Structure

Hofacker, I. (Speaker), Spicher, T. (Contributor), Varenyk, Y. (Contributor), Lorenz, R. (Contributor) & Wolfinger, M. T. (Contributor)

21 Sept 2025

Activity: Talks and presentationsTalk or oral contributionScience to Science


Progress and Challenges in RNA Secondary Structure Prediction

Hofacker, I. (Speaker)

19 Sept 2025

Activity: Talks and presentationsTalk or oral contributionScience to Science


Positional Impacts on tRNA Structure: Constraint-Based Prediction and Links to Modification Sites

Spicher, T. (Speaker), Varenyk, Y. (Contributor), Lorenz, R. (Contributor) & Hofacker, I. (Contributor)

11 Sept 2025

Activity: Talks and presentationsTalk or oral contributionScience to Science


Design of cotranscriptional folding paths

Badelt, S. (Speaker), Miksch , L. (Contributor) & Hofacker, I. (Contributor)

9 Feb 2025

Activity: Talks and presentationsTalk or oral contributionScience to Science


Detecting Pseudouridines in tRNAs: Addressing Computational Mapping Errors

Velandia-Huerto, C. A. (Speaker) & Hofacker, I. (Contributor)

6 Feb 2025

Activity: Talks and presentationsTalk or oral contributionScience to Science


Coarse Grained Sampling of 3D RNA Structures in Ernwin

Hofacker, I. (Speaker)

21 Jul 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Structure and Design of RNase resistant RNA structures

Sidl, L. P. (Speaker) & Hofacker, I. (Contributor)

19 Feb 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Free energy calculation of modified nucleotides by molecular dynamics simulations

Spicher, T. (Speaker), Lorenz, R. (Contributor) & Hofacker, I. (Contributor)

11 Feb 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


The effect of modified nucleotides on RNA structure

Varenyk, Y. (Speaker), Lorenz, R. (Contributor), Spicher, T. (Contributor) & Hofacker, I. (Contributor)

11 Feb 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


The effect of modified nucleotides on RNA structure

Varenyk, Y. (Speaker), Lorenz, R. (Contributor), Spicher, T. (Contributor) & Hofacker, I. (Contributor)

1 Feb 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Computational Estimation of Energy Parameters

Spicher, T. (Speaker), Lorenz, R. (Contributor) & Hofacker, I. (Contributor)

12 Feb 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Modeling RNA-RNA interaction formation on direct paths

Waldl, M. (Speaker), Hofacker, I. (Contributor) & Will, S. (Contributor)

12 Feb 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


The effect of modified nucleotides on secondary structure prediction in tRNA

Varenyk, Y. (Speaker), Hofacker, I. (Contributor), Lorenz, R. (Contributor) & Spicher, T. (Contributor)

12 Feb 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Predicting the effect of modified nucleotides on RNA structure

Hofacker, I. (Invited speaker)

26 Oct 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Computational Estimation of Energy Parameters for modified Nucleotides

Spicher, T. (Speaker), Lorenz, R. (Contributor) & Hofacker, I. (Contributor)

3 Oct 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Incongruent Evolution of RNA Sequence and Structure

Waldl, M. (Speaker), Will, S. (Contributor), Wolfinger, M. T. (Contributor), Hofacker, I. (Contributor) & Stadler, P. (Contributor)

3 Oct 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Modified nucleotides in RNA secondary structure prediction

Varenyk, Y. (Speaker), Hofacker, I. (Contributor), Lorenz, R. (Contributor) & Spicher, T. (Contributor)

3 Oct 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Experiments in Deep Learning for RNA Secondary Structure Prediction

Hofacker, I. (Invited speaker)

18 Sept 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Features of RNA-RNA interaction kinetics

Waldl, M. (Speaker), Will, S. (Contributor) & Hofacker, I. (Contributor)

18 Sept 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Simulations of cotranscriptional folding explain the impact of sequence mutations

Badelt, S. (Speaker), Lorenz, R. (Contributor) & Hofacker, I. (Contributor)

18 Sept 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Experiments in Deep Learning for RNA Secondary Structure Prediction

Hofacker, I. (Keynote speaker)

6 Sept 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


An RNA kinetics ansatz derived from an efficient prediction of RNA pathways

Hofacker, I. (Invited speaker)

7 Aug 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Experiments in Deep Learning for RNA Secondary Structure Prediction

Hofacker, I. (Invited speaker)

7 Aug 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Incongruent Evolution of RNA Sequence and Structure

Waldl, M. (Speaker), Will, S. (Contributor), Hofacker, I. (Contributor) & Stadler, P. (Contributor)

7 Aug 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Modeling RNA-RNA interaction formation on direct paths

Waldl, M. (Speaker), Beckmann-Schneider, I. K. (Contributor), Will, S. (Contributor) & Hofacker, I. (Contributor)

7 Aug 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


MODELING THE KINETICS OF RNA-RNA INTERACTION FORMATION

Waldl, M. (Speaker), Beckmann-Schneider, I. K. (Contributor), Will, S. (Contributor) & Hofacker, I. (Contributor)

17 Nov 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Prediction of co-transcriptional RNA folding for Modeling Riboswitches

Hofacker, I. (Keynote speaker)

7 Oct 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Bi-alignments as Models of Incongruent Evolution of RNA Sequence and Structure

Waldl, M. (Speaker), Will, S. (Contributor), Wolfinger, M. T. (Contributor), Hofacker, I. (Contributor) & Stadler, P. (Contributor)

30 Sept 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Co-transcriptional RNA folding kinetics

Hofacker, I. (Invited speaker)

9 Sept 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Bi-alignments as Models of Incongruent Evolution of RNA Sequence and Structure

Waldl, M. (Contributor), Will, S. (Contributor), Wolfinger, M. T. (Contributor), Hofacker, I. (Speaker) & Stadler, P. (Contributor)

4 Sept 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Human & Bordetella pertussis co-expression networks

Farman, M. R. (Speaker) & Hofacker, I. (Contributor)

10 Feb 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Computational Approaches to RNA Folding Kinetics

Hofacker, I. (Invited speaker)

15 Jan 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


RNA secondary Structures

Hofacker, I. (Invited speaker)

14 Jan 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


RNA-RNA Interaction Kinetics for Refining RNA Targeting Screens

Waldl, M. (Speaker), Will, S. (Contributor) & Hofacker, I. (Contributor)

1 Oct 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


RNA-RNA Interaction Kinetics for Refining RNA Targeting Screens

Waldl, M. (Speaker), Will, S. (Contributor) & Hofacker, I. (Contributor)

25 Sept 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Co-transcriptional Folding Kinetics and Riboswitch Modeling

Hofacker, I. (Invited speaker)

15 Jul 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Identification and Classification of Pseudoknots and their Impact on RNA 3D structure prediction

Beckmann-Schneider, I. K. (Speaker), Thiel, B. (Contributor) & Hofacker, I. (Contributor)

11 Feb 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Predicting Pseudoknots in RNA 3D structures

Beckmann-Schneider, I. K. (Speaker) & Hofacker, I. (Contributor)

2 Oct 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


RNA 2D folding Dynamics and 3D Structure Prediction

Hofacker, I. (Invited speaker)

26 May 2016

Activity: Talks and presentationsTalk or oral contributionOther


Coarse Grain 3D RNA Structure Prediction

Hofacker, I. (Invited speaker)

14 Apr 2016

Activity: Talks and presentationsTalk or oral contributionOther


Computational Biology with RNA Structures, Interactions, and Dynamics

Hofacker, I. (Invited speaker)

9 Jan 2016

Activity: Talks and presentationsTalk or oral contributionOther


Beyond RNA secondary structure

Hofacker, I. (Invited speaker)

28 Jun 2014

Activity: Talks and presentationsTalk or oral contributionOther


siRNA and Oligo Design

Hofacker, I. (Invited speaker)

25 Jun 2014

Activity: Talks and presentationsTalk or oral contributionOther


RNA folding kinetics and energy landscapes

Hofacker, I. (Invited speaker)

24 Jun 2014

Activity: Talks and presentationsTalk or oral contributionOther


Energy directed RNA folding

Hofacker, I. (Invited speaker)

23 Jun 2014

Activity: Talks and presentationsTalk or oral contributionOther


In silico Annotation of noncoding RNAs and their Targets

Hofacker, I. (Invited speaker)

11 Apr 2014

Activity: Talks and presentationsTalk or oral contributionOther


Beyond RNA secondary structure:G-quadruplexes and non-canonical pairs

Hofacker, I. (Invited speaker)

26 Jun 2013

Activity: Talks and presentationsTalk or oral contributionOther


Predicting Targets and Effects of Bacterial small RNAs

Hofacker, I. (Invited speaker)

4 Jun 2013

Activity: Talks and presentationsTalk or oral contributionOther


Predicting functional RNA structures

Hofacker, I. (Speaker)

11 Oct 2012

Activity: Talks and presentationsTalk or oral contributionOther


Folding with Fancy Constraints -Secondary Structures from Probing Data

Hofacker, I. (Speaker)

24 Jul 2012

Activity: Talks and presentationsTalk or oral contributionOther


RNA Structures, Interactions, and Folding Kinetics

Hofacker, I. (Speaker)

4 Jul 2012

Activity: Talks and presentationsTalk or oral contributionOther


Folding Kinetics and Energy Landscapes for RNA Secondary Structures

Hofacker, I. (Speaker)

21 Jun 2012

Activity: Talks and presentationsTalk or oral contributionOther


RNA in silico: Bioinformatik im postgenomischen Zeitalter

Hofacker, I. (Invited speaker)

9 May 2012

Activity: Talks and presentationsTalk or oral contributionOther


RNA Folding Kinetics and Dynamic Landscapes

Hofacker, I. (Speaker)

20 Jan 2012

Activity: Talks and presentationsTalk or oral contributionOther


Advances in RNA Bioinformatics. Prediction of RNA Structures, Interactions, and Folding Kinetics

Hofacker, I. (Speaker)

19 Nov 2011

Activity: Talks and presentationsTalk or oral contributionOther


The art of RNA homology search

Hofacker, I. (Speaker)

15 Nov 2011

Activity: Talks and presentationsTalk or oral contributionOther


Prediction of bacterial small RNA targets

Hofacker, I. (Speaker)

16 Jul 2011

Activity: Talks and presentationsTalk or oral contributionOther


Micro RNA Discovery in Sequencing Data without a Genome

Hofacker, I. (Speaker)

15 Jul 2011

Activity: Talks and presentationsTalk or oral contributionOther


Beyond secondary structures: Predicting non-canonical pairs

Hofacker, I. (Speaker)

26 May 2011

Activity: Talks and presentationsTalk or oral contributionOther


In silico annotation of noncoding RNAs and their targets

Hofacker, I. (Speaker)

13 May 2011

Activity: Talks and presentationsTalk or oral contributionOther


RNA Folding Dynamics -- trajectories and landscapes

Hofacker, I. (Invited speaker)

30 Apr 2010

Activity: Talks and presentationsTalk or oral contributionOther


RNA Genefinding

Hofacker, I. (Invited speaker)

28 Apr 2010

Activity: Talks and presentationsTalk or oral contributionOther


Energy Landscapes for RNA Folding: Time- dependent Landscapes and 2D Projections

Hofacker, I. (Invited speaker)

5 Aug 2009

Activity: Talks and presentationsTalk or oral contributionOther


Bioinformatics for the Modern RNA World:From Gene Finding to Function

Hofacker, I. (Invited speaker)

9 Jul 2009

Activity: Talks and presentationsTalk or oral contributionOther


Detection, annotation, and target search for noncoding RNAs

Hofacker, I. (Invited speaker)

26 Jan 2009

Activity: Talks and presentationsTalk or oral contributionOther


ncRNA Annotation and Target Prediction

Hofacker, I. (Invited speaker)

13 Jan 2009

Activity: Talks and presentationsTalk or oral contributionOther


RNA Bioinformatics: From structure prediction to RNA gene finding

Hofacker, I. (Invited speaker)

12 Nov 2008

Activity: Talks and presentationsTalk or oral contributionOther


Introduction to non-coding RNA gene finding

Hofacker, I. (Invited speaker)

19 Jul 2008

Activity: Talks and presentationsTalk or oral contributionOther


From noncoding RNA Search to Annotation

Hofacker, I. (Invited speaker)

28 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


Prediction of ncRNA Interaction Targets

Hofacker, I. (Invited speaker)

28 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


RNA Structure thermodynamics, basic folding

Hofacker, I. (Invited speaker)

14 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


Solving RNA bioinformatics problems using the Vienna RNA Package

Hofacker, I. (Invited speaker)

14 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


Stochastic Models, HMMs, SCFGs, and model training

Hofacker, I. (Invited speaker)

14 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


Computational Detection and Analysis of noncoding RNAs

Hofacker, I. (Invited speaker)

4 Feb 2008

Activity: Talks and presentationsTalk or oral contributionOther


Prediction of RNA-RNA interaction

Hofacker, I. (Invited speaker)

29 Oct 2007

Activity: Talks and presentationsTalk or oral contributionOther


Prediction of RNA-RNA interaction

Hofacker, I. (Invited speaker)

20 Oct 2007

Activity: Talks and presentationsTalk or oral contributionOther


Computational Detection and Annotation of Non-Coding RNAs

Hofacker, I. (Invited speaker)

30 Sept 2007

Activity: Talks and presentationsTalk or oral contributionOther


Basic Algorithms in RNA Bioinformatics

Hofacker, I. (Invited speaker)

17 Sept 2007

Activity: Talks and presentationsTalk or oral contributionOther


Noncoding RNAs in Bacteria

Hofacker, I. (Invited speaker)

17 Sept 2007

Activity: Talks and presentationsTalk or oral contributionOther


RNA Bioinformatics -- An Overview

Hofacker, I. (Invited speaker)

17 Sept 2007

Activity: Talks and presentationsTalk or oral contributionOther


Prediction of RNA-RNA interaction

Hofacker, I. (Invited speaker)

21 May 2007

Activity: Talks and presentationsTalk or oral contributionOther


RNAdeco: decorating RNA for a purpose

Jantsch, M. F. (Project Coordinator), Ameres, S. (Project Lead) & Hofacker, I. (Project Lead)

1/03/2029/02/28

Project: Research funding


Vorhersage von RNA-RNA Interakt

Hofacker, I. (Project Lead)

1/12/1630/11/20

Project: Research funding


Transcri. Analyse von Bordetell

Hofacker, I. (Project Lead)

29/10/1528/10/18

Project: Research funding


RNA-Funktionskontrolle

Hofacker, I. (Project Lead)

24/03/1123/03/14

Project: Research funding


nicht kodierende RNAs

Hofacker, I. (Project Lead)

1/12/1031/01/19

Project: Research funding


RNA Biology

Leodolter-Barta, A. (Project Lead), von Haeseler, A. (Co-Lead), Bläsi, U. (Project Lead), Görke, B. (Co-Lead), Hofacker, I. (Co-Lead), Moll, I. (Co-Lead), Ayatollahi, Z. (Admin) & Martins, A. (Admin)

1/12/0630/06/21

Project: Research funding


Department of Theoretical Chemistry

Head

Währinger Straße 17
1090 Wien
Room: 306/307

T: +43-1-4277-52738

ivo.hofacker@univie.ac.at