Univ.-Prof. Dipl.-Phys. Dr. Ivo Hofacker
Ivo Hofacker
Summer term 2024
270020 PR Bachelor Laboratory Course D - Theoretical Chemistry and Computational Biological Chemistry
500501 SE Doctoral Research Seminar - Data and Knowledge
Summer term 2023
270020 PR Bachelor Laboratory Course D - Theoretical Chemistry and Computational Biological Chemistry
500501 SE Doctoral Research Seminar - Data and Knowledge
81 - 100 out of 182



Lorenz, R., Bernhart, S. H. F., Externbrink, F., Qin, J., Höner zu Siederdissen, C., Amman, F., Hofacker, I., & Stadler, P. (2012). RNA Folding Algorithms with G-Quadruplexes. In Advances in Bioinformatics and Computational Biology; 7th Brazilian Symposium on Bioinformatics, BSB 2012, Campo Grande, Brazil, August 15-17, 2012. Proceedings (pp. 49-60). Springer-Verlag Berlin. Lecture Notes in Computer Science https://doi.org/10.1007/978-3-642-31927-3_5

Hofacker, I., Reidys, C. M., & Stadler, P. (2012). Symmetric circular matchings and RNA folding. Discrete Mathematics, 312(1), 100-112.

Höner zu Siederdissen, C., Bernhart, S., Stadler, P., & Hofacker, I. (2011). A folding algorithm for extended RNA secondary structures. In Bioinformartics (pp. 129-136). Oxford University Press. Bioinformatics https://doi.org/10.1093/bioinformatics/btr220

Marz, M., Gruber, A., Höner zu Siederdissen, C., Amman, F., Badelt, S., Bartschat, S., Bernhart, S., Kehr, S., Lorenz, R., Tanzer, A., Yusuf, D., Tafer, H., Hofacker, I., & Stadler, P. (2011). Animal snoRNAs and scaRNAs with exceptional structures. RNA Biology, 8(6), 938-946.


Tafer, H., Amman, F., Eggenhofer, F., Stadler, P., & Hofacker, I. (2011). Fast accessibility-based prediction of RNA-RNA interactions. Bioinformatics, 27(14), 1934-1940.


Hackl, M., Jakobi, T., Blom, J., Doppmeier, D., Brinkrolf, K., Bernhart, S., Höner zu Siederdissen, C., Bort, J. A. H., Wieser, M., Kunert, R., Jeffs, S., Hofacker, I., Goesmann, A., Puehler, A., Borth, N., & Grillari, J. (2011). Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: Identification, annotation and profiling of microRNAs as targets for cellular engineering. Journal of Biotechnology, 153(1-2), 62-75.


Washietl, S., Findeiss, S., Müller, S. A., Kalkhof, S., von Bergen, M., Hofacker, I., Stadler, P., & Goldman, N. (2011). RNAcode: Robust discrimination of coding and noncoding regions in comparative sequence data. RNA, 17(4), 578-594. https://doi.org/10.1261/rna.2536111


Kratochvill, F., Machacek, C. N., Vogl, C., Ebner, F. D., Sedlyarov, V., Gruber, A., Hartweger, H., Vielnascher, R., Karaghiosoff, M., Rülicke, T., Müller, M., Hofacker, I., Lang, R., & Kovarik, P. (2011). Tristetraprolin-driven regulatory circuit controls quality and timing of mRNA decay in inflammation. Molecular Systems Biology, 7. https://doi.org/10.1038/msb.2011.93

Lorenz, R., Bernhart, S. H. F., Höner zu Siederdissen, C., Tafer, H., Flamm, C., Stadler, P., & Hofacker, I. (2011). ViennaRNA Package 2.0. Algorithms for Molecular Biology, 6. https://doi.org/10.1186/1748-7188-6-26



Hofacker, I., Stadler, P., & Backofen, R. (2010). Computational studies of non-coding RNAs. In Proceedings of the Pacific Symposion on Biocomputing (pp. 54-56). Unknown publisher.

Gorodkin, J., Hofacker, I., Torarinsson, E., Yao, Z., Havgaard, J. H., & Ruzzo, W. L. (2010). De novo prediction of structured RNAs from genomic sequences. Trends in Biotechnology, 28(1), 9-19. https://doi.org/10.1016/j.tibtech.2009.09.006

81 - 100 out of 182

Computational Estimation of Energy Parameters

Thomas Spicher (Speaker), Ronny Lorenz (Contributor) & Ivo Hofacker (Contributor)

12 Feb 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Modeling RNA-RNA interaction formation on direct paths

Maria Waldl (Speaker), Ivo Hofacker (Contributor) & Sebastian Will (Contributor)

12 Feb 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


The effect of modified nucleotides on secondary structure prediction in tRNA

Yuliia Varenyk (Speaker), Ivo Hofacker (Contributor), Ronny Lorenz (Contributor) & Thomas Spicher (Contributor)

12 Feb 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Predicting the effect of modified nucleotides on RNA structure

Ivo Hofacker (Invited speaker)

26 Oct 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Computational Estimation of Energy Parameters for modified Nucleotides

Thomas Spicher (Speaker), Ronny Lorenz (Contributor) & Ivo Hofacker (Contributor)

3 Oct 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Incongruent Evolution of RNA Sequence and Structure

Maria Waldl (Speaker), Sebastian Will (Contributor), Michael Thomas Wolfinger (Contributor), Ivo Hofacker (Contributor) & Peter Stadler (Contributor)

3 Oct 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Modified nucleotides in RNA secondary structure prediction

Yuliia Varenyk (Speaker), Ivo Hofacker (Contributor), Ronny Lorenz (Contributor) & Thomas Spicher (Contributor)

3 Oct 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Experiments in Deep Learning for RNA Secondary Structure Prediction

Ivo Hofacker (Invited speaker)

18 Sep 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Features of RNA-RNA interaction kinetics

Maria Waldl (Speaker), Sebastian Will (Contributor) & Ivo Hofacker (Contributor)

18 Sep 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Simulations of cotranscriptional folding explain the impact of sequence mutations

Stefan Badelt (Speaker), Ronny Lorenz (Contributor) & Ivo Hofacker (Contributor)

18 Sep 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Experiments in Deep Learning for RNA Secondary Structure Prediction

Ivo Hofacker (Keynote speaker)

6 Sep 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


An RNA kinetics ansatz derived from an efficient prediction of RNA pathways

Ivo Hofacker (Invited speaker)

7 Aug 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Experiments in Deep Learning for RNA Secondary Structure Prediction

Ivo Hofacker (Invited speaker)

7 Aug 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Incongruent Evolution of RNA Sequence and Structure

Maria Waldl (Speaker), Sebastian Will (Contributor), Ivo Hofacker (Contributor) & Peter Stadler (Contributor)

7 Aug 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Modeling RNA-RNA interaction formation on direct paths

Maria Waldl (Speaker), Irene Katharina Beckmann-Schneider (Contributor), Sebastian Will (Contributor) & Ivo Hofacker (Contributor)

7 Aug 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


MODELING THE KINETICS OF RNA-RNA INTERACTION FORMATION

Maria Waldl (Speaker), Irene Katharina Beckmann-Schneider (Contributor), Sebastian Will (Contributor) & Ivo Hofacker (Contributor)

17 Nov 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Prediction of co-transcriptional RNA folding for Modeling Riboswitches

Ivo Hofacker (Keynote speaker)

7 Oct 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Bi-alignments as Models of Incongruent Evolution of RNA Sequence and Structure

Maria Waldl (Speaker), Sebastian Will (Contributor), Michael Thomas Wolfinger (Contributor), Ivo Hofacker (Contributor) & Peter Stadler (Contributor)

30 Sep 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Co-transcriptional RNA folding kinetics

Ivo Hofacker (Invited speaker)

9 Sep 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Bi-alignments as Models of Incongruent Evolution of RNA Sequence and Structure

Maria Waldl (Contributor), Sebastian Will (Contributor), Michael Thomas Wolfinger (Contributor), Ivo Hofacker (Speaker) & Peter Stadler (Contributor)

4 Sep 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Human & Bordetella pertussis co-expression networks

Mariam Rukhama Farman (Speaker) & Ivo Hofacker (Contributor)

10 Feb 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Computational Approaches to RNA Folding Kinetics

Ivo Hofacker (Invited speaker)

15 Jan 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


RNA secondary Structures

Ivo Hofacker (Invited speaker)

14 Jan 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


RNA-RNA Interaction Kinetics for Refining RNA Targeting Screens

Maria Waldl (Speaker), Sebastian Will (Contributor) & Ivo Hofacker (Contributor)

1 Oct 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


RNA-RNA Interaction Kinetics for Refining RNA Targeting Screens

Maria Waldl (Speaker), Sebastian Will (Contributor) & Ivo Hofacker (Contributor)

25 Sep 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Co-transcriptional Folding Kinetics and Riboswitch Modeling

Ivo Hofacker (Invited speaker)

15 Jul 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Identification and Classification of Pseudoknots and their Impact on RNA 3D structure prediction

Irene Katharina Beckmann-Schneider (Speaker), Bernhard Thiel (Contributor) & Ivo Hofacker (Contributor)

11 Feb 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Predicting Pseudoknots in RNA 3D structures

Irene Katharina Beckmann-Schneider (Speaker) & Ivo Hofacker (Contributor)

2 Oct 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


RNA 2D folding Dynamics and 3D Structure Prediction

Ivo Hofacker (Invited speaker)

26 May 2016

Activity: Talks and presentationsTalk or oral contributionOther


Coarse Grain 3D RNA Structure Prediction

Ivo Hofacker (Invited speaker)

14 Apr 2016

Activity: Talks and presentationsTalk or oral contributionOther


Computational Biology with RNA Structures, Interactions, and Dynamics

Ivo Hofacker (Invited speaker)

9 Jan 2016

Activity: Talks and presentationsTalk or oral contributionOther


Beyond RNA secondary structure

Ivo Hofacker (Invited speaker)

28 Jun 2014

Activity: Talks and presentationsTalk or oral contributionOther


siRNA and Oligo Design

Ivo Hofacker (Invited speaker)

25 Jun 2014

Activity: Talks and presentationsTalk or oral contributionOther


RNA folding kinetics and energy landscapes

Ivo Hofacker (Invited speaker)

24 Jun 2014

Activity: Talks and presentationsTalk or oral contributionOther


Energy directed RNA folding

Ivo Hofacker (Invited speaker)

23 Jun 2014

Activity: Talks and presentationsTalk or oral contributionOther


In silico Annotation of noncoding RNAs and their Targets

Ivo Hofacker (Invited speaker)

11 Apr 2014

Activity: Talks and presentationsTalk or oral contributionOther


Beyond RNA secondary structure:G-quadruplexes and non-canonical pairs

Ivo Hofacker (Invited speaker)

26 Jun 2013

Activity: Talks and presentationsTalk or oral contributionOther


Predicting Targets and Effects of Bacterial small RNAs

Ivo Hofacker (Invited speaker)

4 Jun 2013

Activity: Talks and presentationsTalk or oral contributionOther


Predicting functional RNA structures

Ivo Hofacker (Speaker)

11 Oct 2012

Activity: Talks and presentationsTalk or oral contributionOther


Folding with Fancy Constraints -Secondary Structures from Probing Data

Ivo Hofacker (Speaker)

24 Jul 2012

Activity: Talks and presentationsTalk or oral contributionOther


RNA Structures, Interactions, and Folding Kinetics

Ivo Hofacker (Speaker)

4 Jul 2012

Activity: Talks and presentationsTalk or oral contributionOther


Folding Kinetics and Energy Landscapes for RNA Secondary Structures

Ivo Hofacker (Speaker)

21 Jun 2012

Activity: Talks and presentationsTalk or oral contributionOther


RNA in silico: Bioinformatik im postgenomischen Zeitalter

Ivo Hofacker (Invited speaker)

9 May 2012

Activity: Talks and presentationsTalk or oral contributionOther


RNA Folding Kinetics and Dynamic Landscapes

Ivo Hofacker (Speaker)

20 Jan 2012

Activity: Talks and presentationsTalk or oral contributionOther


Advances in RNA Bioinformatics. Prediction of RNA Structures, Interactions, and Folding Kinetics

Ivo Hofacker (Speaker)

19 Nov 2011

Activity: Talks and presentationsTalk or oral contributionOther


The art of RNA homology search

Ivo Hofacker (Speaker)

15 Nov 2011

Activity: Talks and presentationsTalk or oral contributionOther


Prediction of bacterial small RNA targets

Ivo Hofacker (Speaker)

16 Jul 2011

Activity: Talks and presentationsTalk or oral contributionOther


Micro RNA Discovery in Sequencing Data without a Genome

Ivo Hofacker (Speaker)

15 Jul 2011

Activity: Talks and presentationsTalk or oral contributionOther


Beyond secondary structures: Predicting non-canonical pairs

Ivo Hofacker (Speaker)

26 May 2011

Activity: Talks and presentationsTalk or oral contributionOther


In silico annotation of noncoding RNAs and their targets

Ivo Hofacker (Speaker)

13 May 2011

Activity: Talks and presentationsTalk or oral contributionOther


RNA Folding Dynamics -- trajectories and landscapes

Ivo Hofacker (Invited speaker)

30 Apr 2010

Activity: Talks and presentationsTalk or oral contributionOther


RNA Genefinding

Ivo Hofacker (Invited speaker)

28 Apr 2010

Activity: Talks and presentationsTalk or oral contributionOther


Energy Landscapes for RNA Folding: Time- dependent Landscapes and 2D Projections

Ivo Hofacker (Invited speaker)

5 Aug 2009

Activity: Talks and presentationsTalk or oral contributionOther


Bioinformatics for the Modern RNA World:From Gene Finding to Function

Ivo Hofacker (Invited speaker)

9 Jul 2009

Activity: Talks and presentationsTalk or oral contributionOther


Detection, annotation, and target search for noncoding RNAs

Ivo Hofacker (Invited speaker)

26 Jan 2009

Activity: Talks and presentationsTalk or oral contributionOther


ncRNA Annotation and Target Prediction

Ivo Hofacker (Invited speaker)

13 Jan 2009

Activity: Talks and presentationsTalk or oral contributionOther


RNA Bioinformatics: From structure prediction to RNA gene finding

Ivo Hofacker (Invited speaker)

12 Nov 2008

Activity: Talks and presentationsTalk or oral contributionOther


Introduction to non-coding RNA gene finding

Ivo Hofacker (Invited speaker)

19 Jul 2008

Activity: Talks and presentationsTalk or oral contributionOther


From noncoding RNA Search to Annotation

Ivo Hofacker (Invited speaker)

28 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


Prediction of ncRNA Interaction Targets

Ivo Hofacker (Invited speaker)

28 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


RNA Structure thermodynamics, basic folding

Ivo Hofacker (Invited speaker)

14 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


Solving RNA bioinformatics problems using the Vienna RNA Package

Ivo Hofacker (Invited speaker)

14 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


Stochastic Models, HMMs, SCFGs, and model training

Ivo Hofacker (Invited speaker)

14 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


Computational Detection and Analysis of noncoding RNAs

Ivo Hofacker (Invited speaker)

4 Feb 2008

Activity: Talks and presentationsTalk or oral contributionOther


Prediction of RNA-RNA interaction

Ivo Hofacker (Invited speaker)

29 Oct 2007

Activity: Talks and presentationsTalk or oral contributionOther


Prediction of RNA-RNA interaction

Ivo Hofacker (Invited speaker)

20 Oct 2007

Activity: Talks and presentationsTalk or oral contributionOther


Computational Detection and Annotation of Non-Coding RNAs

Ivo Hofacker (Invited speaker)

30 Sep 2007

Activity: Talks and presentationsTalk or oral contributionOther


Basic Algorithms in RNA Bioinformatics

Ivo Hofacker (Invited speaker)

17 Sep 2007

Activity: Talks and presentationsTalk or oral contributionOther


Noncoding RNAs in Bacteria

Ivo Hofacker (Invited speaker)

17 Sep 2007

Activity: Talks and presentationsTalk or oral contributionOther


RNA Bioinformatics -- An Overview

Ivo Hofacker (Invited speaker)

17 Sep 2007

Activity: Talks and presentationsTalk or oral contributionOther


Prediction of RNA-RNA interaction

Ivo Hofacker (Invited speaker)

21 May 2007

Activity: Talks and presentationsTalk or oral contributionOther


RNAdeco: decorating RNA for a purpose

Jantsch, M. F., Ameres, S. & Hofacker, I.

1/03/2029/02/28

Project: Research funding


Vorhersage von RNA-RNA Interakt

Hofacker, I.

1/12/1630/11/20

Project: Research funding


Transcri. Analyse von Bordetell

Hofacker, I.

29/10/1528/10/18

Project: Research funding


RNA-Funktionskontrolle

Hofacker, I.

24/03/1123/03/14

Project: Research funding


nicht kodierende RNAs

Hofacker, I.

1/12/1031/01/19

Project: Research funding


RNA Biology

Leodolter-Barta, A., von Haeseler, A., Bläsi, U., Görke, B., Hofacker, I., Moll, I., Ayatollahi, Z. & Martins, A.

1/12/0630/06/21

Project: Research funding


Department of Theoretical Chemistry

Deputy Head

Währinger Straße 17
1090 Wien
Room: 306/307

T: +43-1-4277-52738

ivo.hofacker@univie.ac.at