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Assoz. Prof. Dipl.-Ing. Markus Muttenthaler, PhD
Markus Muttenthaler
T: +43-1-4277-70515
https://www.neuropeptidelab.com/
Winter term 2024
270011 SE Writing of the Bachelor´s Thesis
270012 PR Elective Laboratory Course for Bachelor Module - Organic/Bioanorganic/Biological/Biophysical Chemistry
270295 VU Chemical Biology
530001 SE Seminar in Chemical Biology for post-graduates
Summer term 2024
270011 SE Writing of the Bachelor´s Thesis
270012 PR Elective Laboratory Course for Bachelor Module - Organic/Bioanorganic/Biological/Biophysical Chemistry
530001 SE Seminar in Chemical Biology for post-graduates
1 - 20 out of 65
Jandl, B., Dighe, S., Baumgartner, M., Makristathis, A., Gasche, C., & Muttenthaler, M. (2024). Gastrointestinal Biofilms: Endoscopic Detection, Disease Relevance, and Therapeutic Strategies. Gastroenterology, 167(6), 1098-1112.e5. https://doi.org/10.1053/j.gastro.2024.04.032
Kremsmayr, T., Schober, G., Kaltenböck, M., Hoare, B. L., Brierley, S. M., & Muttenthaler, M. (2024). Oxytocin Analogues for the Oral Treatment of Abdominal Pain. Angewandte Chemie - International Edition. Advance online publication. https://doi.org/10.1002/anie.202415333
Jandl, B., Dighe, S., Gasche, C., Makristathis, A., & Muttenthaler, M. (2024). Intestinal biofilms: pathophysiological relevance, host defense, and therapeutic opportunities. Clinical microbiology reviews, 37(3), e0013323. Article 00133-23. https://doi.org/10.1128/cmr.00133-23
Jandl, B., Zheng, R., Muttenthaler, M., & Baell, J. (2024). Novel Diacyl-hydrazide Compounds as Potential Therapeutics for Visceral Leishmaniasis. ACS Omega, 9(35), 37170-37182. https://doi.org/10.1021/acsomega.4c04517
Muttenthaler, M. (2024). CHEMICAL STRATEGIES TO TUNE POTENCY, SELECTIVITY AND STABILITY OF VENOM PEPTIDES. Toxicon, 248, Article 108028.
Perisic, M., Kalaba, P., Keimpema, E., Gruber, C. W., & Muttenthaler, M. (2024). Advanced molecular tools to study the oxytocin receptor. Journal of Peptide Science, 30(Suppl. 2), Article YML05.
Jandl, B., Lang, M., Makristathis, A., Gasche, C., & Muttenthaler, M. (2024). Development of gut-restricted antibiofilm peptides to target gastrointestinal biofilms. Journal of Peptide Science, 30(Suppl. 2), Article 248-P1.134.
Raabe, K., Kalaba, P., Yong, X. L. H., Keimpema, E., Anggono, V., & Muttenthaler, M. (2024). Photocontrollable probes for the investigation of neuropeptide signalling. Journal of Peptide Science, 30(Suppl. 2), Article 382-P1.
Perisic, M., Woolcock, K., Hering, A., Mendel, H., & Muttenthaler, M. (2024). Oxytocin and vasopressin signaling in health and disease. Trends in Biochemical Sciences, 49(4), 361-377. https://doi.org/10.1016/j.tibs.2024.01.010
Kalaba, P., Sanchez de la Rosa, C., Möller, A., Alewood, P. F., & Muttenthaler, M. (2024). Targeting the Oxytocin Receptor for Breast Cancer Management: A Niche for Peptide Tracers. Journal of Medicinal Chemistry, 67(3), 1625-1640. https://doi.org/10.1021/acs.jmedchem.3c01089
Orgler, E., Baumgartner, M., Duller, S., Kumptisch, C., Hausmann, B., Moser, D., Khare, V., Lang, M., Köcher, T., Frick, A., Muttenthaler, M., Makristathis, A., Moissl-Eichinger, C., & Gasche, C. (2024). Archaea influence composition of endoscopically visible ileocolonic biofilms. Gut microbes, 16(1), Article 2359500. https://doi.org/10.1080/19490976.2024.2359500
Muratspahić, E., Deibler, K., Han, J., Tomašević, N., Jadhav, K. B., Olivé-Marti, A. L., Hochrainer, N., Hellinger, R., Koehbach, J., Fay, J. F., Rahman, M. H., Hegazy, L., Craven, T. W., Varga, B. R., Bhardwaj, G., Appourchaux, K., Majumdar, S., Muttenthaler, M., Hosseinzadeh, P., ... Gruber, C. W. (2023). Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor. Nature Communications, 14(1), Article 8064. https://doi.org/10.1038/s41467-023-43718-w
Wirth, U., Raabe, K., Kalaba, P., Keimpema, E., Muttenthaler, M., & König, B. (2023). Photoswitchable Probes of Oxytocin and Vasopressin. Journal of Medicinal Chemistry, 66(21), 14853-14865. https://doi.org/10.1021/acs.jmedchem.3c01415
Perisic, M., Kalaba, P., Keimpema, E., Muttenthaler, M., & Gruber, C. (2023). Development and application of fluorescent oxytocin receptor tracers. British Journal of Pharmacology, 180(Supplement1), 694-694. Article Meeting Abstract: P0984.
Raabe, K., & Muttenthaler, M. (2022). Photoactivatable probes to study long-term memory formation. Journal of Peptide Science, 28(3), Article P443.
Jadhav, K. B., Vellan, P., Niederacher, G., Becker, C. F. W., & Muttenthaler, M. (2022). Recombinant- and semi- synthesis of human trefoil factor 2 (hTFF2) protein and its analogues. Journal of Peptide Science, 28(3), Article P429.
Perisic, M., Kalaba, P., Keimpema, E., Gruber, C., & Muttenthaler, M. (2022). Tracer development for oxytocin receptor imaging. Journal of Peptide Science, 28(3), Article P285.
Hering, A., Emidio, N. B., & Muttenthaler, M. (2022). Expanding the versatility and scope of the oxime ligation: rapid bioconjugation to disulfide-rich peptides. Chemical Communications, 58(65), 9100-9103. https://doi.org/10.1039/d2cc03752a
Liu, H., & Muttenthaler, M. (2022). High Oxytocin Receptor Expression Linked to Increased Cell Migration and Reduced Survival in Patients with Triple-Negative Breast Cancer. Biomedicines, 10(7), Article 1595. https://doi.org/10.3390/biomedicines10071595
Hering, A., Jieu, B., Jones, A., & Muttenthaler, M. (2022). Approaches to Improve the Quantitation of Oxytocin in Human Serum by Mass Spectrometry. Frontiers in Chemistry, 10, Article 889154. https://doi.org/10.3389/fchem.2022.889154
1 - 20 out of 65

Transport of bioactive insulin to the intestinal epithelium: Novel oral formulations based on mesoporous silica nanoparticles

Claudia Iriarte Mesa (Speaker), Estelle Juère (Contributor), Andrea Bileck (Contributor), Thomas Kremsmayr (Contributor), Michael L. Goodson (Contributor), Allison Ehrlich (Contributor), Christopher Gerner (Contributor), Hanspeter Kählig (Contributor), Doris Marko (Contributor), Markus Muttenthaler (Contributor), David Berry (Contributor), Giorgia Del Favero (Contributor) & Freddy Kleitz (Contributor)

4 Nov 2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

New opportunities for gut-specific oral peptide drug development

Markus Muttenthaler (Invited speaker)

16 Sept 2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Oral peptide therapeutics for gut disorders

Markus Muttenthaler (Invited speaker)

13 Sept 2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Development of Molecular Tools to Study the Oxytocin Receptor System

Monika Perisic (Speaker), Predrag Kalaba (Contributor), Isabell Ober (Contributor), Erik Keimpema (Contributor), Christian Gruber (Contributor) & Markus Muttenthaler (Contributor)

12 Sept 2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Oral peptide therapeutics for gut disorders

Markus Muttenthaler (Invited speaker)

2 Sept 2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

New Avenues in oral peptide drug development for gut disorders

Markus Muttenthaler (Invited speaker)

25 Aug 2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Oral gut-specific peptide therapeutics for treating gastrointestinal disorders

Markus Muttenthaler (Invited speaker)

29 Feb 2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Oral gut-specific peptide therapeutics for treating gastrointestinal disorders

Markus Muttenthaler (Invited speaker)

27 Feb 2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Oral gut-specific peptide therapeutics for treating gastrointestinal disorders

Markus Muttenthaler (Invited speaker)

15 Feb 2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Development of gut-specific antibiofilm peptides to target mucosal biofilms in patients with gastrointestinal disorders

Bernhard Jandl (Speaker), Michaela Lang (Contributor), Athanasios Makristathis (Contributor), Christoph Gasche (Contributor) & Markus Muttenthaler (Contributor)

24 Nov 2023

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Development of gut-specific antibiofilm peptides to target mucosal biofilms in patients with gastrointestinal disorders

Bernhard Jandl (Speaker), Michaela Lang (Contributor), Athanasios Makristathis (Contributor), Christoph Gasche (Contributor) & Markus Muttenthaler (Contributor)

16 Nov 2023

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Bioactive Peptides – From Nature to Tools and Therapeutics

Markus Muttenthaler (Invited speaker)

15 Oct 2023

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Development of gut-specific antibiofilm peptides to target mucosal biofilms in patients with gastrointestinal disorders

Bernhard Jandl (Speaker), Michaela Lang (Contributor), Athanasios Makristathis (Contributor), Christoph Gasche (Contributor) & Markus Muttenthaler (Contributor)

15 Oct 2023

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Development of gut-specific antibiofilm peptides to target mucosal biofilms in patients with gastrointestinal disorders

Bernhard Jandl (Speaker), Michaela Lang (Contributor), Athanasios Makristathis (Contributor), Christoph Gasche (Contributor) & Markus Muttenthaler (Contributor)

12 Oct 2023

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Trends & opportunities in venom-derived peptide drug development

Markus Muttenthaler (Keynote speaker)

9 Oct 2023

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Dengue NS1 QCM Sensor based on Epitope-imprinted Polymers

K. Sirivibulkovit (Speaker), D. J. Windisch (Contributor), Markus Muttenthaler (Contributor), P. Saetear (Contributor) & Peter Lieberzeit (Contributor)

4 Aug 2023

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Gut-specific peptide therapeutics

Markus Muttenthaler (Invited speaker)

14 Jul 2023

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Towards gut-specific antibiofilm peptides to target mucosal biofilms in patients with gastrointestinal disorders

Bernhard Jandl (Speaker), Michaela Lang (Contributor), Athanasios Makristathis (Contributor), Christoph Gasche (Contributor) & Markus Muttenthaler (Contributor)

7 Jul 2023

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Chemical strategies to target mucosal biofilms in patients with gastrointestinal disorders

Bernhard Jandl (Speaker) & Markus Muttenthaler (Contributor)

27 Apr 2023

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Development of Photoactivatable Neuropeptide Probes

Konstantin Raabe (Speaker), Predrag Kalaba (Contributor), Erik Keimpema (Contributor) & Markus Muttenthaler (Contributor)

22 Mar 2023

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Gut-specific peptide therapeutics

Markus Muttenthaler (Invited speaker)

28 Feb 2023

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Gut-specific peptide therapeutics

Markus Muttenthaler (Speaker)

23 Feb 2023

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Fluorescent peptide tracers for oxytocin receptor visualization

Monika Perisic (Speaker), Predrag Kalaba (Contributor), C.W. Gruber (Contributor) & Markus Muttenthaler (Contributor)

1 Dec 2022

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Gut-specific peptide therapeutics

Markus Muttenthaler (Speaker)

13 Nov 2022

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Gut-stable peptide therapeutics

Markus Muttenthaler (Speaker)

28 Aug 2022

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Molecular strategies to tune venom peptide functionality

Markus Muttenthaler (Keynote speaker)

7 Aug 2022

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Gut-specific peptide therapeutics

Markus Muttenthaler (Invited speaker)

4 Aug 2022

Activity: Talks and presentations › Talk or oral contribution › Science to Science

From Venoms to Neuropeptides – Molecular Tools for Neuroscience

Markus Muttenthaler (Invited speaker)

16 Jun 2022

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Gut-specific peptide therapeutics

Markus Muttenthaler (Keynote speaker)

29 May 2022

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Molecular strategies to study and treat gastrointestinal disorders

Markus Muttenthaler (Invited speaker)

17 May 2022

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Molecular strategies to study and treat gastrointestinal disorders

Markus Muttenthaler (Invited speaker)

15 May 2022

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Biologically active oxytocin probes allow (sub)-cellular receptor localization

Monika Perisic (Speaker), Predrag Kalaba (Contributor), Erik Keimpema (Contributor), Thomas Kremsmayr (Contributor), Satish Dighe (Contributor), Christian Gruber (Contributor), Katsuhiko Nishimori (Contributor) & Markus Muttenthaler (Contributor)

12 May 2022

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Chemical strategies to tune potency, selectivity and stability of neuropeptides

Markus Muttenthaler (Speaker)

4 Oct 2021

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Exploring natural scaffolds to engineer gut-stable peptide ligands

Thomas Kremsmayr (Speaker), Christian Friedrich Wilhelm Becker (Contributor) & Markus Muttenthaler (Contributor)

5 Dec 2019

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Disulfide bonds – folding, stability and mimetics

Markus Muttenthaler (Invited speaker)

5 Sept 2019

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Multivalent Ligand Design – Chemistry and Applications

Markus Muttenthaler (Speaker)

3 Dec 2018

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Chemical strategies to tune potency, selectivity and stability of neuropeptides

Markus Muttenthaler (Speaker)

28 Nov 2018

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Recombinant synthesis and purification of hTFF2 protein in S. Cerevisiae

Kirtikumar Bhaskarrao Jadhav (Speaker), Gerhard Niederacher (Contributor) & Markus Muttenthaler (Contributor)

26 Aug 2018

Activity: Talks and presentations › Talk or oral contribution › Science to Science

From venoms to drugs

Markus Muttenthaler (Invited speaker)

25 Jun 2018

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Neuropeptide Research – From Molecular Probes to Therapeutic Leads

Markus Muttenthaler (Invited speaker)

30 Oct 2017

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Multivalent Ligand Design – Chemistry and Applications

Markus Muttenthaler (Speaker)

12 Oct 2017

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Molecular probe development for the Oxytocin/Vasopressin signalling system - from nature’s blueprints to chemical engineering’

Markus Muttenthaler (Invited speaker)

27 Jul 2017

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Department of Biological Chemistry

Währinger Straße 38-42
1090 Wien
Room: 1H38

T: +43-1-4277-70515

markus.muttenthaler@univie.ac.at