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Assoz. Prof. Dr. Thomas Mindt, Privatdoz.

T: +43-1-4277-52684

thomas.mindt@univie.ac.at

Summer term 2023

270011 SE Writing of the Bachelor´s Thesis

270012 PR Elective Laboratory Course for Bachelor Module - Organic/Bioanorganic/Biological/Biophysical Chemistry

270041 VO Medical Radiochemistry II - Tracer Development - from Bench to Bed

270165 VO Chemistry of Actinides

270192 PR Practical Course Radiopharmaceutical Chemistry

270304 PR Practical Course Bio Inorganic Chemistry

530014 SE PhD / MSc Seminar Radiopharmaceutical Chemistry

530015 SE Journal Club Radiopharmaceutical Chemistry

Winter term 2022

270011 SE Writing of the Bachelor´s Thesis

270012 PR Elective Laboratory Course for Bachelor Module - Organic/Bioanorganic/Biological/Biophysical Chemistry

270054 VO General Chemistry A

270186 PR Practical Course Coordination Chemistry

270192 PR Practical Course Radiopharmaceutical Chemistry

270203 VO Medical Radio Chemistry 1 - Medicinal Radiochemistry I

270304 PR Practical Course Bio Inorganic Chemistry

270315 VO Radioactive Metals in Medicine

530014 SE PhD / MSc Seminar Radiopharmaceutical Chemistry

530015 SE Journal Club Radiopharmaceutical Chemistry

Summer term 2022

270011 SE Writing of the Bachelor´s Thesis

270012 PR Elective Laboratory Course for Bachelor Module - Organic/Bioanorganic/Biological/Biophysical Chemistry

270023 UE Inorganic Chemistry Lab course D - Inorganic Chemistry Lab course IIID - Coordination chemistry

270035 VO Medical Radiochemistry II - Tracer Development - from Bench to Bed

270097 VO Chemistry of Actinides

270100 UE Inorganic Chemistry Lab course A - Inorganic Chemistry Lab course III A - Bioinorganic Chemistry, coordination chemistry

270215 SE PhD / MSc Seminar

Jouini, N., Cardinale, J., & Mindt, T. L. (2022). Evaluation of a Radiolabeled Macrocyclic Peptide as Potential PET Imaging Probe for PD-L1. ChemMedChem, 17(12), [e202200091]. https://doi.org/10.1002/cmdc.202200091

Rischka, L., Vraka, C., Pichler, V., Rasul, S., Nics, L., Gryglewski, G., Handschuh, P., Murgas, M., Godbersen, G. M., Silberbauer, L. R., Unterholzner, J., Wotawa, C., Haider, A., Ahmed, H., Schibli, R., Mindt, T., Mitterhauser, M., Wadsak, W., Hahn, A., ... Ametamey, S. M. (2022). First-in-Humans Brain PET Imaging of the GluN2B-Containing N-methyl-D-aspartate Receptor with (R)-C-11-Me-NB1. Journal of Nuclear Medicine, 63(6), 936-941. https://doi.org/10.2967/jnumed.121.262427

Giammei, C., Jouini, N., Brandt, M. R., Frey, S., Mindt, T. L., & Cardinale, J. (2022). Unexpected transformation of n.c.a. [ ¹¹¹In]InCl ₃ in stock solutions into an unreactive [ ¹¹¹In]In-species. Applied Radiation and Isotopes, 180, [110037]. https://doi.org/10.1016/j.apradiso.2021.110037

Rischka, L., Murgaš, M., Pichler, V., Vraka, C., Rausch, I., Winkler, D., Nics, L., Rasul, S., Silberbauer, L. R., Reed, M. B., Godbersen, G. M., Unterholzner, J., Handschuh, P., Gryglewski, G., Mindt, T., Mitterhauser, M., Hahn, A., Ametamey, S. M., Wadsak, W., ... Hacker, M. (2022). Biodistribution and dosimetry of the GluN2B-specific NMDA receptor PET radioligand (R)-[¹¹C]Me-NB1. EJNMMI Research, 12(1), [53]. https://doi.org/10.1186/s13550-022-00925-8

Klasen, B., Lemcke, D., Mindt, T. L., Gasser, G., & Roesch, F. (2021). Development and in vitro evaluation of new bifunctional ⁸⁹Zr-chelators based on the 6-amino-1,4-diazepane scaffold for immuno-PET applications. Nuclear Medicine and Biology, 102-103, 12-23. https://doi.org/10.1016/j.nucmedbio.2021.06.007

Rischka, L., Vraka, C., Pichler, V., Rasul, S., Nics, L., Gryglewski, G., Handschuh, P., Murgas, M., Godbersen, G. M., Silberbauer, L. R., Unterholzner, J., Wotawa, C., Haider, A., Ahmed, H., Schibli, R., Mindt, T., Mitterhauser, M., Wadsak, W., Hahn, A., ... Ametamey, S. M. (2021). First-in-human mapping of the GluN2B subunits of the N-methyl-D-aspartate receptor using (R)-[(11)Cc]Me-NB1 and PET. European Journal of Nuclear Medicine and Molecular Imaging, 48(SUPPL 1), 296.

Feiner, I. V. J., Brandt, M., Cowell, J., Demuth, T., Vugts, D., Gasser, G., & Mindt, T. L. (2021). The Race for Hydroxamate-Based Zirconium-89 Chelators. Cancers, 13(17), [4466]. https://doi.org/10.3390/cancers13174466

Grob, N. M., Schibli, R., Behe, M., & Mindt, T. L. (2021). Improved Tumor-Targeting with Peptidomimetic Analogs of Minigastrin Lu-177-PP-F11N. Cancers, 13(11), [2629]. https://doi.org/10.3390/cancers13112629

Grob, N. M., Schibli, R., Behe, M., Valverde, I. E., & Mindt, T. L. (2021). 1,5-Disubstituted 1,2,3-Triazoles as Amide Bond Isosteres Yield Novel Tumor-Targeting Minigastrin Analogs. ACS Medicinal Chemistry Letters , 12(4), 585-592. https://doi.org/10.1021/acsmedchemlett.0c00636

Vrettos, E., Valverde, I. E., Mascarin, A., Pallier, P. N., Cerofolini, L., Fragai, M., Parigi, G., Hirmiz, B., Bekas, N., Grob, N. M., Shaye, H., Del Borgo, M., Aguilar, M., Magnani, F., Syed, N., Crook, T., Waqif, E., Ghazaly, E., Cherezov, V., ... Stylos, E. K. (2020). Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity. Chemistry: A European Journal, 26(47), 10690-10694. https://doi.org/10.1002/chem.202000924

Recnik, L-M., Kandioller, W., & Mindt, T. L. (2020). 1,4-Disubstituted 1,2,3-Triazoles as Amide Bond Surrogates for the Stabilisation of Linear Peptides with Biological Activity. Molecules, 25(16), [3576]. https://doi.org/10.3390/molecules25163576

Brandt, M., Cowell, J., Aulsebrook, M. L., Gasser, G., & Mindt, T. L. (2020). Radiolabelling of the octadentate chelators DFO* and oxoDFO* with zirconium-89 and gallium-68. Journal of Biological Inorganic Chemistry, 25, 789-796. https://doi.org/10.1007/s00775-020-01800-4

Giammei, C., Balber, T., Benčurová, K., Cardinale, J., Berroterán-Infante, N., Brandt, M., Jouini, N., Hacker, M., Mitterhauser, M., & Mindt, T. L. (2020). Sorbitol as a Polar Pharmacological Modifier to Enhance the Hydrophilicity of ^99mTc-Tricarbonyl-Based Radiopharmaceuticals. Molecules (Basel, Switzerland), 25(11), [2680]. https://doi.org/10.3390/molecules25112680

Grob, N. M., Schmid, S., Schibli, R., Behe, M., & Mindt, T. L. (2020). Design of Radiolabeled Analogs of Minigastrin by Multiple Amide-to-Triazole Substitutions. Journal of Medicinal Chemistry, 63(9), 4496-4505. https://doi.org/10.1021/acs.jmedchem.9b01937

Grob, N. M., Haussinger, D., Deupi, X., Schibli, R., Behe, M., & Mindt, T. L. (2020). Triazolo-Peptidomimetics: Novel Radiolabeled Minigastrin Analogs for Improved Tumor Targeting. Journal of Medicinal Chemistry, 63(9), 4484-4495. https://doi.org/10.1021/acs.jmedchem.9b01936

Brandt, M., Cardinale, J., Rausch, I., & Mindt, T. L. (2019). Manganese in PET imaging: Opportunities and challenges. Journal of Labelled Compounds and Radiopharmaceuticals, 62(8), 541-551. https://doi.org/10.1002/jlcr.3754

Brandt, M., Cardinale, J., Giammei, C., Guarrochena, X., Happl, B., Jouini, N., & Mindt, T. L. (2019). Mini-review: Targeted radiopharmaceuticals incorporating reversible, low molecular weight albumin binders. Nuclear Medicine and Biology, 70, 46-52. https://doi.org/10.1016/j.nucmedbio.2019.01.006