Richter, P., Karanth, S., dos Santos Natividade, R., Nicoli, A., Kogut-Guenthel, M. M., Benthin, J., Di Pizio, A., Koehler, M., & Somoza, V. (2025). Biomolecular and biophysical AFM probing reveals distinct binding of bitter peptide VAPFPEVF to TAS2R16 without inducing an intracellular calcium response. Food Chemistry, 484, Article 144448. https://doi.org/10.1016/j.foodchem.2025.144448

Gradl, K., Richter, P., & Somoza, V. (2025). Bitter peptides formed during in-vitro gastric digestion induce mechanisms of gastric acid secretion and release satiating serotonin via bitter taste receptors TAS2R4 and TAS2R43 in human parietal cells in culture. Food Chemistry, 482, Article 144174. https://doi.org/10.1016/j.foodchem.2025.144174

Boger, V., Pirkwieser, P., Orth, N., Koehler, M., & Somoza, V. (2025). AFM-optimized single-cell level LA-ICP-MS imaging for quantitative mapping of intracellular zinc concentration in immobilized human parietal cells using gelatin droplet-based calibration. Analytica Chimica Acta, 1355, Article 343999. https://doi.org/10.1016/j.aca.2025.343999

Tiroch, J., Dunkel, A., Sterneder, S. K., Zehentner, S., Behrens, M., DiPizio, A., Ley, J. P., Lieder, B., & Somoza, V. (2024). A NOVEL CELL MODEL FOR BITTER TASTE THRESHOLD PREDICTION BASED ON INTERLEUKIN-6 RELEASE IN HUMAN GINGIVAL FIBROBLASTS. Chemical Senses, 49, Article Meeting Abstract bjae039.03.

Richter, P., Sebald, K., Fischer, K., Schnieke, A. E., Jlilati, M., Mittermeier-Klessinger, V., & Somoza, V. (2024). BITTER PEPTIDES DERIVED FROM GASTRIC DIGESTION OF SWEET-TASTING THAUMATIN AMELIORATE H. PYLORI INDUCED PRO-INFLAMMATORY IL-17A RELEASE VIA BITTER TASTE RECEPTOR TAS2R16. Chemical Senses, 49, Article Meeting Abstract bjae039.03.

Zehentner, S., Mistlberger-Reiner, A., Wachter, E., Bacovsky, K., Friedrich, M., Pirkwieser, P., Orth, N., Boger, V., Kahlenberg, K., Kreißl, J., Rust, P., Pils, S., Grimm, C., Ley, J. P., & Somoza, V. (2024). HOMOERIODICTYOL COUNTERACTS THE BITTERNESS RESPONSE ELICITED BY PT-BASED CHEMOTHERAPEUTICS IN A CELLULAR MODEL SYSTEM AND REDUCES BITTER PHANTOGEUSIA IN CANCER PATIENTS. Chemical Senses, 49, Article Meeting Abstract bjae039.18.

Gradl, K., & Somoza, V. (2024). HUMAN PARIETAL CELLS IN CULTURE RELEASE SATIATING SEROTONIN IN RESPONSE TO BITTER PEPTIDES FORMED DURING DIGESTION OF PEA PROTEIN HYDROLYSATES, AND DEMONSTRATE ENHANCED MECHANISMS OF GASTRIC ACID SECRETION VIA BITTER TASTE RECEPTORS TAS2R4 AND TAS2R43. Chemical Senses, 49, Article Meeting Abstract bjae039.07.

Danzer, B., Jukic, M., Dunkel, A., Andersen, G., Lieder, B., Schaudy, E., Stadlmayr, S., Lietard, J., Michel, T., Krautwurst, D., Haller, B., Knolle, P., Somoza, M. M., Lingor, P., & Somoza, V. (2024). IMPAIRED IRON GLUCONATE IDENTIFICATION IN SARS-COV-2 IGG⁺ SUBJECTS AND ASSOCIATED LOWER TRANSCRIPT LEVELS OF THE HUMAN FOLIATE PAPILLAE TONGUE TRANSCRIPTOME. Chemical Senses, 49, Article Meeting Abstract bjae039.10.

Danzer, B., Jukic, M., Dunkel, A., Andersen, G., Lieder, B., Schaudy, E., Stadlmayr, S., Lietard, J., Michel, T., Krautwurst, D., Haller, B., Knolle, P., Somoza, M., Lingor, P., & Somoza, V. (2024). Impaired metal perception and regulation of associated human foliate papillae tongue transcriptome in long-COVID-19. Scientific Reports, 14(1), Article 15408. https://doi.org/10.1038/s41598-024-66079-w

Sterneder, S., Seitz, J., Kiefl, J., Rottmann, E., Liebig, M., Blings, M., Seilwind, S., Zhou, Y., Wei, J., Guan, H., Zhu, Q., Kreißl, J., Lamottke, K., Ley, J. P., & Somoza, V. (2024). Identification of 4′-Demethyl-3,9-dihydroeucomin as a Bitter-Masking Compound from the Resin of Daemonorops draco. Journal of Agricultural and Food Chemistry, 72(38), 20991-20999. https://doi.org/10.1021/acs.jafc.4c04583

Richter, P., Sebald, K., Fischer, K., Schnieke, A., Jlilati, M., Mittermeier-Klessinger, V., & Somoza, V. (2024). Gastric digestion of the sweet-tasting plant protein thaumatin releases bitter peptides that reduce H. pylori induced pro-inflammatory IL-17A release via the TAS2R16 bitter taste receptor. Food Chemistry, 448, Article 139157. https://doi.org/10.1016/j.foodchem.2024.139157

Mueller, A. U., Andersen, G., Richter, P., & Somoza, V. (2024). Activation of the TRPML1 Ion Channel Induces Proton Secretion in the Human Gastric Parietal Cell Line HGT-1. International Journal of Molecular Sciences, 25(16), Article 8829. https://doi.org/10.3390/ijms25168829

Walser, C., Spaccasassi, A., Gradl, K., Stark, T. D., Sterneder, S., Wolter, F. P., Achatz, F., Frank, O., Somoza, V., Hofmann, T., & Dawid, C. (2024). Human Sensory, Taste Receptor, and Quantitation Studies on Kaempferol Glycosides Derived from Rapeseed/Canola Protein Isolates. Journal of Agricultural and Food Chemistry, 72(26), 14830-14843. https://doi.org/10.1021/acs.jafc.4c02342

Karanth, S., Benthin, J., Wiesenfarth, M., Somoza, V., & Koehler, M. (2024). Nanodisc Technology: Direction toward Physicochemical Characterization of Chemosensory Membrane Proteins in Food Flavor Research. Journal of Agricultural and Food Chemistry, 72(26), 14521-14529. https://doi.org/10.1021/acs.jafc.4c01827

Sternberg, F., Wimmer, M., Arapovic, J., Hommel, T., Panteva, V., Gregor, A., Duszka, K., Kofler, B., Somoza, V., & König, J. (2024). Systemic metabolic effects of medium-chain fatty acids supplementation: insights from murine models. FEBS Open Bio, 14(Supplement: 2), 43-43. Article ShT-03.4-3.

Preinfalk, V., Kimmeswenger, I., Somoza, V., & Lieder, B. (2024). Dipeptidyl-peptidase 4 (DPP4) mediates fatty acid uptake inhibition by glucose via TAS1R3 and GLUT-2 in Caco-2 enterocytes. Heliyon, 10(9), Article e30329. https://doi.org/10.1016/j.heliyon.2024.e30329

Koehler, M., Benthin, J., Karanth, S., Wiesenfarth, M., Sebald, K., & Somoza, V. (2024). Biophysical investigations using atomic force microscopy can elucidate the link between mouthfeel and flavour perception. Nature Food, 5(4), 281-287. https://doi.org/10.1038/s43016-024-00958-3

Richter, P., Andersen, G., Kahlenberg, K., Mueller, A. U., Pirkwieser, P., Boger, V., & Somoza, V. (2024). Sodium-Permeable Ion Channels TRPM4 and TRPM5 are Functional in Human Gastric Parietal Cells in Culture and Modulate the Cellular Response to Bitter-Tasting Food Constituents. Journal of Agricultural and Food Chemistry, 72(9), 4906-4917. https://doi.org/10.1021/acs.jafc.3c09085

Gradl, K., Sánchez Hernández, A. S., Grayson, W. L., Finnigan, T. JA., Theobald, H. E., Kashi, B., & Somoza, V. (2024). What Technological and Economic Elements Must be Addressed to Support the Affordability, Accessibility, and Desirability of Alternative Proteins in LMIC? Current Developments in Nutrition, 8, Article 102027. https://doi.org/10.1016/j.cdnut.2023.102027

Cervantes Recalde, M. F., Schmidt, J., Girardi, C., Massironi, M., Rechl, M. L., Hans, J., Stuhlmann, D., Somoza, V., & Lieder, B. (2024). Capsaicin attenuates the effect of inflammatory cytokines in a HaCaT cell model for basal keratinocytes. Frontiers in Pharmacology, 15, Article 1474898. https://doi.org/10.3389/fphar.2024.1474898