Gaider, M., Kimmeswenger, I., Schmidt, J., Thines, C., Wu, A., Stoffl, T. K., Rust, P., Ley, J. P., Krammer, G. E., Somoza, V., & Lieder, B. (2025). Sucrose reduction with maintained sweetness level lowers glycemic fluctuations and energy intake in healthy males. Frontiers in Nutrition, 12, Article 1682297. https://doi.org/10.3389/fnut.2025.1682297

Kimmeswenger, I., Groessing, F., Preinfalk, V., Gregor, A., Dunkel, A., Schaudy, E., Mistlberger-Reiner, A. T., Rechl, M. L., Somoza, M. M., Koenig, J., Somoza, V., Duszka, K., & Lieder, B. (2025). Weight loss induced by calorie restriction in mice is associated with a higher sweet taste response and increased fungiform papillae density. Appetite, 214, Article 108215. https://doi.org/10.1016/j.appet.2025.108215

Orth, H. N., Pirkwieser, P., Giridhar, M., Boger, V., Somoza, M. M., Dunkel, A., & Somoza, V. (2025). Bitter Taste Receptors TAS2R8 and TAS2R10 Reduce Proton Secretion and Differentially Modulate Cadmium Uptake in Immortalized Human Gastric Cells. International Journal of Molecular Sciences, 26(18), Article 9166. https://doi.org/10.3390/ijms26189166

Richter, P., Karanth, S., dos Santos Natividade, R., Nicoli, A., Kogut-Guenthel, M. M., Benthin, J., Di Pizio, A., Koehler, M., & Somoza, V. (2025). Biomolecular and biophysical AFM probing reveals distinct binding of bitter peptide VAPFPEVF to TAS2R16 without inducing an intracellular calcium response. Food Chemistry, 484, Article 144448. https://doi.org/10.1016/j.foodchem.2025.144448

Gradl, K., Richter, P., & Somoza, V. (2025). Bitter peptides formed during in-vitro gastric digestion induce mechanisms of gastric acid secretion and release satiating serotonin via bitter taste receptors TAS2R4 and TAS2R43 in human parietal cells in culture. Food Chemistry, 482, Article 144174. https://doi.org/10.1016/j.foodchem.2025.144174

Cervantes Recalde, M. F., Bogensperger, E. Z., Hans, J., Stuhlmann, D., Somoza, V., & Lieder, B. (2025). Role of homovanillic acid esters in the regulation of skin inflammatory pathways and their effect on tight junction protein expression. Frontiers in Pharmacology, 16, Article 1629941. https://doi.org/10.3389/fphar.2025.1629941

Orth, H. N., Pirkwieser, P., Benthin, J., Koehler, M., Sterneder, S., Parlar, E., Schaudy, E., Lietard, J., Michel, T., Boger, V., Dunkel, A., Somoza, M. M., & Somoza, V. (2025). Bitter Taste Receptor TAS2R43 Co-Regulates Mechanisms of Gastric Acid Secretion and Zinc Homeostasis. International Journal of Molecular Sciences, 26(13), Article 6017. https://doi.org/10.3390/ijms26136017

Boger, V., Pirkwieser, P., Orth, N., Koehler, M., & Somoza, V. (2025). AFM-optimized single-cell level LA-ICP-MS imaging for quantitative mapping of intracellular zinc concentration in immobilized human parietal cells using gelatin droplet-based calibration. Analytica Chimica Acta, 1355, Article 343999. https://doi.org/10.1016/j.aca.2025.343999

Dos Santos Natividade, R., Danzer, B., Somoza, V., & Koehler, M. (2025). Atomic force microscopy at the forefront: unveiling foodborne viruses with biophysical tools. Npj viruses, 3(1), 25. https://doi.org/10.1038/s44298-025-00107-y

Gradl, K., Sterneder, S., Kahlenberg, K., Brandl, B., Skurk, T., & Somoza, V. (2025). Randomized Controlled Trial: Effects of a Bitter-Tasting Pea Protein Hydrolysate Intervention With Low Degree of Hydrolyzation on Energy Intake in Moderately Overweight Male Subjects. Molecular Nutrition and Food Research, Article e70195. Advance online publication. https://doi.org/10.1002/mnfr.70195

Tiroch, J., Dunkel, A., Sterneder, S. K., Zehentner, S., Behrens, M., DiPizio, A., Ley, J. P., Lieder, B., & Somoza, V. (2024). A NOVEL CELL MODEL FOR BITTER TASTE THRESHOLD PREDICTION BASED ON INTERLEUKIN-6 RELEASE IN HUMAN GINGIVAL FIBROBLASTS. Chemical Senses, 49, Article Meeting Abstract bjae039.03.

Richter, P., Sebald, K., Fischer, K., Schnieke, A. E., Jlilati, M., Mittermeier-Klessinger, V., & Somoza, V. (2024). BITTER PEPTIDES DERIVED FROM GASTRIC DIGESTION OF SWEET-TASTING THAUMATIN AMELIORATE H. PYLORI INDUCED PRO-INFLAMMATORY IL-17A RELEASE VIA BITTER TASTE RECEPTOR TAS2R16. Chemical Senses, 49, Article Meeting Abstract bjae039.03.

Zehentner, S., Mistlberger-Reiner, A., Wachter, E., Bacovsky, K., Friedrich, M., Pirkwieser, P., Orth, N., Boger, V., Kahlenberg, K., Kreißl, J., Rust, P., Pils, S., Grimm, C., Ley, J. P., & Somoza, V. (2024). HOMOERIODICTYOL COUNTERACTS THE BITTERNESS RESPONSE ELICITED BY PT-BASED CHEMOTHERAPEUTICS IN A CELLULAR MODEL SYSTEM AND REDUCES BITTER PHANTOGEUSIA IN CANCER PATIENTS. Chemical Senses, 49, Article Meeting Abstract bjae039.18.

Gradl, K., & Somoza, V. (2024). HUMAN PARIETAL CELLS IN CULTURE RELEASE SATIATING SEROTONIN IN RESPONSE TO BITTER PEPTIDES FORMED DURING DIGESTION OF PEA PROTEIN HYDROLYSATES, AND DEMONSTRATE ENHANCED MECHANISMS OF GASTRIC ACID SECRETION VIA BITTER TASTE RECEPTORS TAS2R4 AND TAS2R43. Chemical Senses, 49, Article Meeting Abstract bjae039.07.

Danzer, B., Jukic, M., Dunkel, A., Andersen, G., Lieder, B., Schaudy, E., Stadlmayr, S., Lietard, J., Michel, T., Krautwurst, D., Haller, B., Knolle, P., Somoza, M. M., Lingor, P., & Somoza, V. (2024). IMPAIRED IRON GLUCONATE IDENTIFICATION IN SARS-COV-2 IGG⁺ SUBJECTS AND ASSOCIATED LOWER TRANSCRIPT LEVELS OF THE HUMAN FOLIATE PAPILLAE TONGUE TRANSCRIPTOME. Chemical Senses, 49, Article Meeting Abstract bjae039.10.

Danzer, B., Jukic, M., Dunkel, A., Andersen, G., Lieder, B., Schaudy, E., Stadlmayr, S., Lietard, J., Michel, T., Krautwurst, D., Haller, B., Knolle, P., Somoza, M., Lingor, P., & Somoza, V. (2024). Impaired metal perception and regulation of associated human foliate papillae tongue transcriptome in long-COVID-19. Scientific Reports, 14(1), Article 15408. https://doi.org/10.1038/s41598-024-66079-w

Sterneder, S., Seitz, J., Kiefl, J., Rottmann, E., Liebig, M., Blings, M., Seilwind, S., Zhou, Y., Wei, J., Guan, H., Zhu, Q., Kreißl, J., Lamottke, K., Ley, J. P., & Somoza, V. (2024). Identification of 4′-Demethyl-3,9-dihydroeucomin as a Bitter-Masking Compound from the Resin of Daemonorops draco. Journal of Agricultural and Food Chemistry, 72(38), 20991-20999. https://doi.org/10.1021/acs.jafc.4c04583

Richter, P., Sebald, K., Fischer, K., Schnieke, A., Jlilati, M., Mittermeier-Klessinger, V., & Somoza, V. (2024). Gastric digestion of the sweet-tasting plant protein thaumatin releases bitter peptides that reduce H. pylori induced pro-inflammatory IL-17A release via the TAS2R16 bitter taste receptor. Food Chemistry, 448, Article 139157. https://doi.org/10.1016/j.foodchem.2024.139157

Mueller, A. U., Andersen, G., Richter, P., & Somoza, V. (2024). Activation of the TRPML1 Ion Channel Induces Proton Secretion in the Human Gastric Parietal Cell Line HGT-1. International Journal of Molecular Sciences, 25(16), Article 8829. https://doi.org/10.3390/ijms25168829

Walser, C., Spaccasassi, A., Gradl, K., Stark, T. D., Sterneder, S., Wolter, F. P., Achatz, F., Frank, O., Somoza, V., Hofmann, T., & Dawid, C. (2024). Human Sensory, Taste Receptor, and Quantitation Studies on Kaempferol Glycosides Derived from Rapeseed/Canola Protein Isolates. Journal of Agricultural and Food Chemistry, 72(26), 14830-14843. https://doi.org/10.1021/acs.jafc.4c02342