Details

[Back]

Assoz. Prof. Dipl.-Ing. Markus Muttenthaler, PhD

T: +43-1-4277-70515

markus.muttenthaler@univie.ac.at

https://www.neuropeptidelab.com/

Summer term 2024

270011 SE Writing of the Bachelor´s Thesis

270012 PR Elective Laboratory Course for Bachelor Module - Organic/Bioanorganic/Biological/Biophysical Chemistry

530001 SE Seminar in Chemical Biology for post-graduates

Winter term 2023

270011 SE Writing of the Bachelor´s Thesis

270012 PR Elective Laboratory Course for Bachelor Module - Organic/Bioanorganic/Biological/Biophysical Chemistry

270295 VU Chemical Biology

530001 SE Seminar in Chemical Biology for post-graduates

Summer term 2023

270011 SE Writing of the Bachelor´s Thesis

270012 PR Elective Laboratory Course for Bachelor Module - Organic/Bioanorganic/Biological/Biophysical Chemistry

530001 SE Seminar in Chemical Biology for post-graduates

Busnelli, M., Kleinau, G., Muttenthaler, M., Stoev, S., Manning, M., Bibic, L., Howell, L. A., McCormick, P. J., Di Lascio, S., Braida, D., Sala, M., Rovati, G. E., Bellini, T., & Chini, B. (2016). Design and Characterization of Superpotent Bivalent Ligands Targeting Oxytocin Receptor Dimers via a Channel-Like Structure. Journal of Medicinal Chemistry, 59(15), 7152-7166. https://doi.org/10.1021/acs.jmedchem.6b00564

Muttenthaler, M., Albericio, F., & Dawson, P. E. (2015). Methods, setup and safe handling for anhydrous hydrogen fluoride cleavage in Boc solid-phase peptide synthesis. Nature Protocols, 10(7), 1067-1083. https://doi.org/10.1038/nprot.2015.061

Arranz-Gibert, P., Guixer, B., Malakoutikhah, M., Muttenthaler, M., Guzman, F., Teixido, M., & Giralt, E. (2015). Lipid Bilayer Crossing-The Gate of Symmetry. Water-Soluble Phenylproline-Based Blood-Brain Barrier Shuttles. Journal of the American Chemical Society, 137(23), 7357-7364. https://doi.org/10.1021/jacs.5b02050

Akondi, K. B., Muttenthaler, M., Dutertre, S., Kaas, Q., Craik, D. J., Lewis, R. J., & Alewood, P. F. (2014). Discovery, Synthesis, and Structure Activity Relationships of Conotoxins. Chemical Reviews, 114(11), 5815-5847. https://doi.org/10.1021/cr400401e

de Araujo, A. D., Mobli, M., Castro, J., Harrington, A. M., Vetter, I., Dekan, Z., Muttenthaler, M., Wan, J., Lewis, R. J., King, G. F., Brierley, S. M., & Alewood, P. F. (2014). Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain. Nature Communications, 5, [3165]. https://doi.org/10.1038/ncomms4165

Koehbach, J., O'Brien, M., Muttenthaler, M., Miazzo, M., Akcan, M., Elliott, A. G., Daly, N. L., Harvey, P. J., Arrowsmith, S., Gunasekera, S., Smith, T. J., Wray, S., Goransson, U., Dawson, P. E., Craik, D. J., Freissmuth, M., & Gruber, C. W. (2013). Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 110(52), 21183-21188. https://doi.org/10.1073/pnas.1311183110

Gemmill, K. B., Muttenthaler, M., Delehanty, J. B., Stewart, M. H., Susumu, K., Dawson, P. E., & Medintz, I. L. (2013). Evaluation of diverse peptidyl motifs for cellular delivery of semiconductor quantum dots. Analytical and Bioanalytical Chemistry, 405(19), 6145-6154. https://doi.org/10.1007/s00216-013-6982-2

Koehbach, J., Stockner, T., Bergmayr, C., Muttenthaler, M., & Gruber, C. W. (2013). Insights into the molecular evolution of oxytocin receptor ligand binding. Biochemical Society Transactions, 41, 197-+. https://doi.org/10.1042/BST20120256

Gruber, C. W., Koehbach, J., & Muttenthaler, M. (2012). Exploring bioactive peptides from natural sources for oxytocin and vasopressin drug discovery. Future Medicinal Chemistry, 4(14), 1791-1798. https://doi.org/10.4155/fmc.12.108

Gruber, C. W., & Muttenthaler, M. (2012). Discovery of defense- and neuropeptides in social ants by genome-mining. PLoS ONE, 7(3), [e32559]. https://doi.org/10.1371/journal.pone.0032559

Muttenthaler, M., Dutertre, S., Wingerd, J. S., Aini, J. W., Walton, H., Alewood, P. F., & Lewis, R. J. (2012). Abundance and diversity of Conus species (Gastropoda: Conidae) at the northern tip of New Ireland province of Papua New Guinea. NAUTILUS , 126(2), 47–56.

Muttenthaler, M., Akondi, K. B., & Alewood, P. F. (2011). Structure-activity studies on alpha-conotoxins. Current Pharmaceutical Design, 17(38), 4226-4241. https://doi.org/10.2174/138161211798999384

Mobli, M., Morgenstern, D., King, G. F., Alewood, P. F., & Muttenthaler, M. (2011). Site-specific pK(a) determination of selenocysteine residues in selenovasopressin by using 77Se NMR spectroscopy. Angewandte Chemie (International Edition), 50(50), 11952-5. https://doi.org/10.1002/anie.201104169

Gruber, C. W., Muttenthaler, M., & Freissmuth, M. (2010). Ligand-Based Peptide Design and Combinatorial Peptide Libraries to Target G Protein-Coupled Receptors. Current Pharmaceutical Design, 16(28), 3071-3088.

Muttenthaler, M. M., de Araujo, A. D., Andersson, A., Vetter, I., Gruber, C. W., Feytens, D., Bergmayr, C., Freissmuth, M., Lewis, R., & Alewood, P. (2010). Oxytocin Agonist Design - A selenocysteine mimetic reveals a functional selectivity switch for the human oxytocin receptor. Journal of Peptide Science, 16(Suppl. 1), 161. https://doi.org/10.1002/psc.1303

Development of gut-specific antibiofilm peptides to target mucosal biofilms in patients with gastrointestinal disorders

Bernhard Jandl (Speaker), Michaela Lang (Contributor), Athanasios Makristathis (Contributor), Christoph Gasche (Contributor) & Markus Muttenthaler (Contributor)

24 Nov 2023