Details

Assoz. Prof. Mark Manuel Somoza, Privatdoz. B.Sc. MSc PhD

T: +43-1-4277-52643

mark.somoza@univie.ac.at

Huertas-Díaz, L., Vestergaard, L. G., Marietou, A., Irla, M., Behr, J., Somoza, M. M., Feilberg, A., & Schwab, C. (2025). Insights into the utilisation of 1,2-propanediol and interactions with the cell envelope of Clostridium perfringens. Gut Pathogens, 17(1), Article 23. https://doi.org/10.1186/s13099-025-00689-1

Santhosh, S., Istvánffy, S., Sabary, O., Yaakobi, E., Giridhar, M., Behr, J., & Somoza, M. M. (2025). Efficiency of Digital Photolithographic Synthesis of Large, High-Quality DNA Libraries and Microarrays using a Guanine O⁶Dephosphitylation Strategy. Communications Chemistry, 8(1), Article 321. https://doi.org/10.1038/s42004-025-01755-0

Kimmeswenger, I., Groessing, F., Preinfalk, V., Gregor, A., Dunkel, A., Schaudy, E., Mistlberger-Reiner, A. T., Rechl, M. L., Somoza, M. M., Koenig, J., Somoza, V., Duszka, K., & Lieder, B. (2025). Weight loss induced by calorie restriction in mice is associated with a higher sweet taste response and increased fungiform papillae density. Appetite, 214, Article 108215. https://doi.org/10.1016/j.appet.2025.108215

Orth, H. N., Pirkwieser, P., Giridhar, M., Boger, V., Somoza, M. M., Dunkel, A., & Somoza, V. (2025). Bitter Taste Receptors TAS2R8 and TAS2R10 Reduce Proton Secretion and Differentially Modulate Cadmium Uptake in Immortalized Human Gastric Cells. International Journal of Molecular Sciences, 26(18), Article 9166. https://doi.org/10.3390/ijms26189166

Orth, H. N., Pirkwieser, P., Benthin, J., Koehler, M., Sterneder, S., Parlar, E., Schaudy, E., Lietard, J., Michel, T., Boger, V., Dunkel, A., Somoza, M. M., & Somoza, V. (2025). Bitter Taste Receptor TAS2R43 Co-Regulates Mechanisms of Gastric Acid Secretion and Zinc Homeostasis. International Journal of Molecular Sciences, 26(13), Article 6017. https://doi.org/10.3390/ijms26136017

Michel, T., Behr, J., Sabzalipoor, H., Ibanez Redin, G. G., Lietard, J., Schletterer, T., Funck, M., & Somoza, M. M. (2025). Color-corrected and high-contrast catadioptric relay for maskless high-resolution nucleic acid photolithography. Optics Express, 33(8), 17068-17084. https://doi.org/10.1364/OE.557937

Danzer, B., Jukic, M., Dunkel, A., Andersen, G., Lieder, B., Schaudy, E., Stadlmayr, S., Lietard, J., Michel, T., Krautwurst, D., Haller, B., Knolle, P., Somoza, M. M., Lingor, P., & Somoza, V. (2024). IMPAIRED IRON GLUCONATE IDENTIFICATION IN SARS-COV-2 IGG⁺ SUBJECTS AND ASSOCIATED LOWER TRANSCRIPT LEVELS OF THE HUMAN FOLIATE PAPILLAE TONGUE TRANSCRIPTOME. Chemical Senses, 49, Article Meeting Abstract bjae039.10.

Danzer, B., Jukic, M., Dunkel, A., Andersen, G., Lieder, B., Schaudy, E., Stadlmayr, S., Lietard, J., Michel, T., Krautwurst, D., Haller, B., Knolle, P., Somoza, M., Lingor, P., & Somoza, V. (2024). Impaired metal perception and regulation of associated human foliate papillae tongue transcriptome in long-COVID-19. Scientific Reports, 14(1), Article 15408. https://doi.org/10.1038/s41598-024-66079-w

Schaudy, E., Ibanez Redin, G. G., Parlar, E., Somoza, M. M., & Lietard, J. (2024). Nonaqueous Oxidation in DNA Microarray Synthesis Improves the Oligonucleotide Quality and Preserves Surface Integrity on Gold and Indium Tin Oxide Substrates. Analytical Chemistry, 96(6), 2378-2386. https://doi.org/10.1021/acs.analchem.3c04166

Das, A., Santhosh, S., Giridhar, M., Behr, J., Michel, T., Schaudy, E., Ibanez Redin, G. G., Lietard, J., & Somoza, M. M. (2023). Dipodal Silanes Greatly Stabilize Glass Surface Functionalization for DNA Microarray Synthesis and High-Throughput Biological Assays. Analytical Chemistry, 95(41), 15384-15393. https://doi.org/10.1021/acs.analchem.3c03399

Schaudy, E., Lietard, J., & Somoza, M. M. (2023). Enzymatic Synthesis of High-Density RNA Microarrays. Current protocols, 3(2), Article e667. https://doi.org/10.1002/cpz1.667

Schaudy, E., Hölz, K., Lietard, J., & Somoza, M. M. (2022). Simple synthesis of massively parallel RNA microarrays via enzymatic conversion from DNA microarrays. Nature Communications, 13(1), Article 3772. https://doi.org/10.1038/s41467-022-31370-9

Lietard, J., Ameur, D., & Somoza, M. M. (2022). Sequence-dependent quenching of fluorescein fluorescence on single-stranded and double-stranded DNA. Rsc advances, 12(9), 5629-5637. https://doi.org/10.1039/d2ra00534d

Kolton, M., Weston, D. J., Mayali, X., Weber, P. K., McFarlane, K. J., Pett-Ridge, J., Somoza, M. M., Lietard, J., Glass, J. B., Lilleskov, E. A., Shaw, A. J., Tringe, S., Hanson, P. J., & Kostka, J. E. (2022). Defining the Sphagnum Core Microbiome across the North American Continent Reveals a Central Role for Diazotrophic Methanotrophs in the Nitrogen and Carbon Cycles of Boreal Peatland Ecosystems. mBio, 13(1), Article e03714-21. https://doi.org/10.1128/MBIO.03714-21

Lieder, B., Conka, J., Mistlberger-Reiner, A., Zabel, V., Ameur, D., Somoza, M. M., Sebekova, K., Celec, P., & Somoza, V. (2022). Long-Term Consumption of a Sugar-Sweetened Soft Drink in Combination with a Western-Type Diet Is Associated with Morphological and Molecular Changes of Taste Markers Independent of Body Weight Development in Mice. Nutrients, 14(3), Article 594. https://doi.org/10.3390/nu14030594

Tiroch, J., Sterneder, S., Di Pizio, A., Lieder, B., Hoelz, K., Holik, A. K., Pignitter, M., Behrens, M., Somoza, M., Ley, J. P., & Somoza, V. (2021). Bitter Sensing TAS2R50 Mediates the trans-Resveratrol-Induced Anti-inflammatory Effect on Interleukin 6 Release in HGF-1 Cells in Culture. Journal of Agricultural and Food Chemistry, 69(45), 13339-13349. https://doi.org/10.1021/acs.jafc.0c07058

Schaudy, E., Lietard, J., & Somoza, M. M. (2021). Sequence Preference and Initiator Promiscuity for De Novo DNA Synthesis by Terminal Deoxynucleotidyl Transferase. ACS Synthetic Biology, 10(7), 1750-1760. https://doi.org/10.1021/acssynbio.1c00142

Lietard, J., Leger, A., Erlich, Y., Sadowski, N., Timp, W., & Somoza, M. M. (2021). Chemical and photochemical error rates in light-directed synthesis of complex DNA libraries. Nucleic Acids Research, 49(12), 6687-6701. https://doi.org/10.1093/nar/gkab505

Holik, A.-K., Schweiger, K., Stoeger, V., Lieder, B., Reiner, A., Zopun, M., Hoi, J. K., Kretschy, N., Somoza, M. M., Kriwanek, S., Pignitter, M., & Somoza, V. (2021). Gastric Serotonin Biosynthesis and Its Functional Role in L-Arginine-Induced Gastric Proton Secretion. International Journal of Molecular Sciences, 22(11), Article 5881. https://doi.org/10.3390/ijms22115881

Schaudy, E., Somoza, M. M., & Lietard, J. (2020). l-DNA Duplex Formation as a Bioorthogonal Information Channel in Nucleic Acid-Based Surface Patterning. Chemistry: A European Journal, 26(63), 14310-14314. https://doi.org/10.1002/chem.202001871

Applications and Challenges of Composite DNA Letters for High-Density Information Encoding

Istvánffy, S. (Speaker), Sabzalipoor, H. (Contributor), Preuss, I. (Contributor), Shafir, R. (Contributor), Gilboar, M. R. (Contributor), Yakoobi, E. (Contributor), Yakhini , Z. (Contributor) & Somoza, M. M. (Contributor)

29 Sept 2025