Details

Assoz. Prof. Mark Manuel Somoza, Privatdoz. B.Sc. MSc PhD

T: +43-1-4277-52643

mark.somoza@univie.ac.at

Summer term 2022

270165 VO+SE Nucleic Acid Biotechnology

Schaudy, E., Hölz, K., Lietard, J., & Somoza, M. M. (2022). Simple synthesis of massively parallel RNA microarrays via enzymatic conversion from DNA microarrays. Nature Communications, 13(1), [3772]. https://doi.org/10.1038/s41467-022-31370-9

Lietard, J., Ameur, D., & Somoza, M. M. (2022). Sequence-dependent quenching of fluorescein fluorescence on single-stranded and double-stranded DNA. Rsc advances, 12(9), 5629-5637. https://doi.org/10.1039/d2ra00534d

Kolton, M., Weston, D. J., Mayali, X., Weber, P. K., McFarlane, K. J., Pett-Ridge, J., Somoza, M. M., Lietard, J., Glass, J. B., Lilleskov, E. A., Shaw, A. J., Tringe, S., Hanson, P. J., & Kostka, J. E. (2022). Defining the Sphagnum Core Microbiome across the North American Continent Reveals a Central Role for Diazotrophic Methanotrophs in the Nitrogen and Carbon Cycles of Boreal Peatland Ecosystems. mBio, 13(1), [e03714-21]. https://doi.org/10.1128/MBIO.03714-21

Lieder, B., Conka, J., Mistlberger-Reiner, A., Zabel, V., Ameur, D., Somoza, M. M., Sebekova, K., Celec, P., & Somoza, V. (2022). Long-Term Consumption of a Sugar-Sweetened Soft Drink in Combination with a Western-Type Diet Is Associated with Morphological and Molecular Changes of Taste Markers Independent of Body Weight Development in Mice. Nutrients, 14(3), [594]. https://doi.org/10.3390/nu14030594

Tiroch, J., Sterneder, S., Di Pizio, A., Lieder, B., Hoelz, K., Holik, A. K., Pignitter, M., Behrens, M., Somoza, M., Ley, J. P., & Somoza, V. (2021). Bitter Sensing TAS2R50 Mediates the trans-Resveratrol-Induced Anti-inflammatory Effect on Interleukin 6 Release in HGF-1 Cells in Culture. Journal of Agricultural and Food Chemistry, 69(45), 13339-13349. https://doi.org/10.1021/acs.jafc.0c07058

Schaudy, E., Lietard, J., & Somoza, M. M. (2021). Sequence Preference and Initiator Promiscuity for De Novo DNA Synthesis by Terminal Deoxynucleotidyl Transferase. ACS Synthetic Biology, 10(7), 1750-1760. https://doi.org/10.1021/acssynbio.1c00142

Lietard, J., Leger, A., Erlich, Y., Sadowski, N., Timp, W., & Somoza, M. M. (2021). Chemical and photochemical error rates in light-directed synthesis of complex DNA libraries. Nucleic Acids Research, 49(12), 6687-6701. https://doi.org/10.1093/nar/gkab505

Holik, A-K., Schweiger, K., Stoeger, V., Lieder, B., Reiner, A., Zopun, M., Hoi, J. K., Kretschy, N., Somoza, M. M., Kriwanek, S., Pignitter, M., & Somoza, V. (2021). Gastric Serotonin Biosynthesis and Its Functional Role in L-Arginine-Induced Gastric Proton Secretion. International Journal of Molecular Sciences, 22(11), [5881]. https://doi.org/10.3390/ijms22115881

Schaudy, E., Somoza, M. M., & Lietard, J. (2020). l-DNA Duplex Formation as a Bioorthogonal Information Channel in Nucleic Acid-Based Surface Patterning. Chemistry: A European Journal, 26(63), 14310-14314. https://doi.org/10.1002/chem.202001871

Antkowiak, P. L., Lietard, J., Darestani, M. Z., Somoza, M. M., Stark, W. J., Heckel, R., & Grass, R. N. (2020). Low cost DNA data storage using photolithographic synthesis and advanced information reconstruction and error correction. Nature Communications, 11(1), [5345]. https://doi.org/10.1038/s41467-020-19148-3

Walker, J. M., Mennella, I., Ferracane, R., Tagliamonte, S., Holik, A-K., Hoelz, K., Somoza, M. M., Somoza, V., Fogliano, V., & Vitaglione, P. (2020). Melanoidins from coffee and bread differently influence energy intake: A randomized controlled trial of food intake and gut-brain axis response. Journal of Functional Foods, 72, [104063]. https://doi.org/10.1016/j.jff.2020.104063

Stoeger, V., Holik, A-K., Hoelz, K., Dingjan, T., Hans, J., Ley, J. P., Krammer, G. E., Niv, M. Y., Somoza, M. M., & Somoza, V. (2020). Bitter-Tasting Amino Acids L-Arginine and L-Isoleucine Differentially Regulate Proton Secretion via T2R1 Signaling in Human Parietal Cells in Culture. Journal of Agricultural and Food Chemistry, 68(11), 3434-3444. https://doi.org/10.1021/acs.jafc.9b06285

Hoelz, K., Pavlic, A., Lietard, J., & Somoza, M. M. (2019). Specificity and Efficiency of the Uracil DNA Glycosylase-Mediated Strand Cleavage Surveyed on Large Sequence Libraries. Scientific Reports, 9(1), [17822]. https://doi.org/10.1038/s41598-019-54044-x

Lietard, J., Damha, M. J., & Somoza, M. M. (2019). Large-Scale Photolithographic Synthesis of Chimeric DNA/RNA Hairpin Microarrays To Explore Sequence Specificity Landscapes of RNase HII Cleavage. Biochemistry, 58(44), 4389-4397. https://doi.org/10.1021/acs.biochem.9b00806

Zaunschirm, M., Pignitter, M., Kopic, A., Kessler, C., Hochkogler, C., Kretschy, N., Somoza, M. M., & Somoza, V. (2019). Exposure of Human Gastric Cells to Oxidized Lipids Stimulates Pathways of Amino Acid Biosynthesis on a Genomic and Metabolomic Level. Molecules, 24(22), [4111]. https://doi.org/10.3390/molecules24224111

Hoi, J. K., Lieder, B., Pignitter, M., Hans, J., Ley, J. P., Lietard, J., Hoelz, K., Somoza, M., & Somoza, V. (2019). Identification of Cinnamaldehyde as Most Effective Fatty Acid Uptake Reducing Cinnamon-Derived Compound in Differentiated Caco-2 Cells Compared to Its Structural Analogues Cinnamyl Alcohol, Cinnamic Acid, and Cinnamyl Isobutyrate. Journal of Agricultural and Food Chemistry, 67(42), 11638-11649. https://doi.org/10.1021/acs.jafc.9b04274

Hoelz, K., Schaudy, E., Lietard, J., & Somoza, M. M. (2019). Multi-level patterning nucleic acid photolithography. Nature Communications, 10(1), [3805]. https://doi.org/10.1038/s41467-019-11670-3

Mayali, X., Weber, P. K., Nuccio, E., Lietard, J., Somoza, M., Blazewicz, S. J., & Pett-Ridge, J. (2019). Chip-SIP: Stable Isotope Probing Analyzed with rRNA-Targeted Microarrays and NanoSIMS. In M. Dumont, & M. Hernández García (Eds.), Stable Isotope Probing: Methods and Protocols (Vol. 2046, pp. 71-87). Springer-Nature. Methods in Molecular Biology Vol. 2046 https://doi.org/10.1007/978-1-4939-9721-3_6

Lietard, J., Schaudy, E., Hölz, K., Ameur, D., & Somoza, M. M. (2019). High-Density DNA and RNA microarrays - Photolithographic Synthesis, Hybridization and Preparation of Large Nucleic Acid Libraries. Journal of Visualized Experiments, (150), [e59936]. https://doi.org/10.3791/59936

Lietard, J., & Somoza, M. M. (2019). Spotting, Transcription and In Situ Synthesis: Three Routes for the Fabrication of RNA Microarrays. Computational and Structural Biotechnology Journal, 17, 862-868. https://doi.org/10.1016/j.csbj.2019.06.004

Sequence-Dependent Fluorescence for Greenscale Imaging Technology on DNA Microarrays

Tadija Kekic (Speaker) & Mark Manuel Somoza (Contributor)

19 Sep 2022

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Bitter sensing TAS2R50 mediates trans-Resveratrol-induced anti-inflammatory effect on interleukin 6 release in HGF-1 cells

Veronika Somoza (Speaker), Johanna Tiroch (Contributor), Sonja Katharina Sterneder (Contributor), Antonella Di Pizio (Contributor), Barbara Lieder (Contributor), Kathrin Hölz (Contributor), Ann-Katrin Holik (Contributor), Marc Pignitter (Contributor), Maik Behrens (Contributor), Mark Manuel Somoza (Contributor) & Jakob Ley (Contributor)

21 Aug 2022

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Next Gen Science”-Session: “Light-Directed Synthesis of Complex Nucleic Acid Libraries"

Erika Schaudy (Speaker) & Mark Manuel Somoza (Contributor)

26 Jun 2022

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Bioanalytical applications of nucleic acid photolithography

Mark Manuel Somoza (Invited speaker)

29 Jun 2021

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Ultra-large scale photolithographic synthesis of nucleic acids

Mark Manuel Somoza (Invited speaker)

19 May 2021

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Impact of NƐ-Carboxymethyllysine on serotonin release from differentiated Caco-2cells

Ann-Katrin Holik (Speaker), Barbara Lieder (Contributor), Nicole Kretschy (Contributor), Mark Manuel Somoza (Contributor), Jakob P. Ley (Contributor), Joachim Hans (Contributor) & Veronika Somoza (Contributor)

25 Aug 2017

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Fabrication of Thrombin-binding aptamers containing 2'-Fluoroarabinonucleic acids (2'F-ANAs) on High-Density DNA Microarrays

Mark Manuel Somoza (Contributor)

19 Jul 2016

Activity: Talks and presentations › Talk or oral contribution › Other

Nonivamide, a capsaicin analog, increases dopamine and serotonin release in SH-SY5Y cells via a TRPV1- independent pathway

Mark Manuel Somoza (Contributor)

22 Aug 2012

Activity: Talks and presentations › Talk or oral contribution › Other

In situ, light-directed synthesis of high-density RNA microarrays

Mark Manuel Somoza (Invited speaker)

29 Sep 2011

Activity: Talks and presentations › Talk or oral contribution › Other

In situ, light-directed synthesis of high-density RNA microarrays

Mark Manuel Somoza (Speaker)

4 Sep 2011

Activity: Talks and presentations › Talk or oral contribution › Other

In situ, light-directed synthesis of high-density RNA microarrays

Mark Manuel Somoza (Speaker)

30 Jun 2011

Activity: Talks and presentations › Talk or oral contribution › Other

Synthesis of High-Density RNA Microarrays

Mark Manuel Somoza (Invited speaker)

5 Jun 2011

Activity: Talks and presentations › Talk or oral contribution › Other

Ribosomal Synthesis of High Density Peptide Microarrays

4/09/17 → 3/09/22

Project: Research funding

Enzymatische Synthese

15/10/14 → 15/10/17

Project: Research funding

RNA Microarrays

11/10/11 → 8/01/17

Project: Research funding

Department of Inorganic Chemistry

Josef-Holaubek-Platz 2 (UZA II)
1090 Wien
Room: 2A553

T: +43-1-4277-52643

mark.somoza@univie.ac.at