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Dr. Tilman Grune
Wintersemester 2024
Sommersemester 2024
Wintersemester 2023
Valeanu, A., Margina, D., Weber, D., Stuetz, W., Moreno-Villanueva, M., Dollé, M. E. T., Jansen, E. HJM., Gonos, E. S., Bernhardt, J., Grubeck-Loebenstein, B., Weinberger, B., Fiegl, S., Sikora, E., Mosieniak, G., Toussaint, O., Debacq-Chainiaux, F., Capri, M., Garagnani, P., Pirazzini, C., ... Gradinaru, D. (2024). Development and validation of cardiometabolic risk predictive models based on LDL oxidation and candidate geromarkers from the MARK-AGE data. Mechanisms of Ageing and Development, 222, Artikel 111987. https://doi.org/10.1016/j.mad.2024.111987



Clemen, R., Dethloff, W., Berner, J., Schulan, P., Martinet, A., Weltmann, K. D., von Woedtke, T., Grune, T., Wende, K., & Bekeschus, S. (2024). Insulin oxidation and oxidative modifications alter glucose uptake, cell metabolism, and inflammatory secretion profiles. Redox biology, 77, Artikel 103372. https://doi.org/10.1016/j.redox.2024.103372

Schoissengeier, V., Maqboul, L., Weber, D., Grune, T., Bürkle, A., Moreno-Villaneuva, M., Franceschi, C., Capri, M., Bernhard, J., Toussaint, O., Debacq-Chainiaux, F., Weinberger, B., Gonos, E. S., Sikora, E., Dollé, M., Jansen, E., Slagboom, P. E., Hervonnen, A., Hurme, M., ... Wagner, K.-H. (2024). Association between bilirubin and biomarkers of metabolic health and oxidative stress in the MARK-AGE cohort. Iscience, 27(7), 110234. Artikel 110234. https://doi.org/10.1016/j.isci.2024.110234

Leist, M., Buettner, A., Diel, P., Eisenbrand, G., Epe, B., Först, P., Grune, T., Haller, D., Heinz, V., Hellwig, M., Humpf, H. U., Jäger, H., Kulling, S. E., Mally, A., Marko, D., Nöthlings, U., Röhrdanz, E., Spranger, J., Vieths, S., ... Hengstler, J. G. (2024). Controversy on health-based guidance values for bisphenol A—the need of criteria for studies that serve as a basis for risk assessment. Archives of Toxicology, 98(7), 1967-1973. https://doi.org/10.1007/s00204-024-03778-3


Pellowski, D., Kusch, P., Henning, T., Kochlik, B., Maares, M., Schmiedeskamp, A., Pohl, G., Schreiner, M., Baldermann, S., Haase, H., Schwerdtle, T., Grune, T., & Weber, D. (2024). Postprandial Micronutrient Variability and Bioavailability: An Interventional Meal Study in Young vs. Old Participants. Nutrients, 16(5), Artikel 625. https://doi.org/10.3390/nu16050625

Hellwig, M., Diel, P., Eisenbrand, G., Grune, T., Guth, S., Henle, T., Humpf, H. U., Joost, H. G., Marko, D., Raupbach, J., Roth, A., Vieths, S., & Mally, A. (2024). Dietary glycation compounds–implications for human health. Critical Reviews in Toxicology, 54(8), 485-617. https://doi.org/10.1080/10408444.2024.2362985

Fernando, R., Shindyapina, A. V., Ost, M., Santesmasses, D., Hu, Y., Tyshkovskiy, A., Yim, S. H., Weiss, J., Gladyshev, V. N., Grune, T., & Castro, J. P. (2023). Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. Communications Biology, 6(1), Artikel 1240. https://doi.org/10.1038/s42003-023-05595-3



Henning, T., Wagner, P., Gedat, E., Kochlik, B., Kusch, P., Sowoidnich, K., Vastag, M., Gleim, J., Braune, M., Maiwald, M., Sumpf, B., Grune, T., & Weber, D. (2023). Evaluation of Modern Approaches for the Assessment of Dietary Carotenoids as Markers for Fruit and Vegetable Consumption. Nutrients, 15(7), Artikel 1665. https://doi.org/10.3390/nu15071665

Guth, S., Baum, M., Cartus, A. T., Diel, P., Engel, K. H., Engeli, B., Epe, B., Grune, T., Haller, D., Heinz, V., Hellwig, M., Hengstler, J. G., Henle, T., Humpf, H. U., Jäger, H., Joost, H. G., Kulling, S. E., Lachenmeier, D. W., Lampen, A., ... Eisenbrand, G. (2023). Evaluation of the genotoxic potential of acrylamide: Arguments for the derivation of a tolerable daily intake (TDI value). Food and Chemical Toxicology, 173, Artikel 113632. https://doi.org/10.1016/j.fct.2023.113632

Campolo, N., Mastrogiovanni, M., Mariotti, M., Issoglio, F. M., Estrin, D., Hägglund, P., Grune, T., Davies, M. J., Bartesaghi, S., & Radi, R. (2023). Multiple oxidative post-translational modifications of human glutamine synthetase mediate peroxynitrite-dependent enzyme inactivation and aggregation. Journal of Biological Chemistry, 299(3), Artikel 102941. https://doi.org/10.1016/j.jbc.2023.102941

Skipitari, M., Kalaitzopoulou, E., Papadea, P., Varemmenou, A., Gavriil, V. E., Sarantopoulou, E., Cefalas, A. C., Tsakas, S., Rosmaraki, E., Margiolaki, I., Grune, T., & Georgiou, C. D. (2023). Titanium dioxide nanoparticle-based hydroxyl and superoxide radical production for oxidative stress biological simulations. Journal of Photochemistry and Photobiology A: Chemistry, 435, Artikel 114290. https://doi.org/10.1016/j.jphotochem.2022.114290

Kananen, L., Hurme, M., Buerkle, A., Moreno-Villanueva, M., Bernhardt, J., Debacq-Chainiaux, F., Grubeck-Loebenstein, B., Malavolta, M., Basso, A., Piacenza, F., Collino, S., Gonos, E. S., Sikora, E., Gradinaru, D., Jansen, E. H. J. M., Dolle, M. E. T., Salmon, M., Stuetz, W., Weber, D., ... Jylhava, J. (2023). Circulating cell-free DNA in health and disease - the relationship to health behaviours, ageing phenotypes and metabolomics. GeroScience, 45(1), 85-103. https://doi.org/10.1007/s11357-022-00590-8

Kochlik, B., Franz, K., Henning, T., Weber, D., Wernitz, A., Herpich, C., Jannasch, F., Aykac, V., Mueller-Werdan, U., Schulze, M. B., Grune, T., & Norman, K. (2023). Frailty is characterized by biomarker patterns reflecting inflammation or muscle catabolism in multi-morbid patients. Journal of Cachexia, Sarcopenia and Muscle, 14(1), 157-166. https://doi.org/10.1002/jcsm.13118

Giacconi, R., D'Aquila, P., Malavolta, M., Piacenza, F., Burkle, A., Villanueva, M. M., Dolle, M. E. T., Jansen, E., Grune, T., Gonos, E. S., Franceschi, C., Capri, M., Gradinaru, D., Grubeck-Loebenstein, B., Sikora, E., Stuetz, W., Weber, D., Toussaint, O., Debacq-Chainiaux, F., ... Provinciali, M. (2023). Bacterial DNAemia in Older Participants and Nonagenarian Offspring and Association With Redox Biomarkers: Results From MARK-AGE Study. Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, 78(1), 42-50. Artikel glac154. https://doi.org/10.1093/gerona/glac154


Role of lipofuscin in oxidative stress, lysosomal dysfunction, and cell death

Tim Baldensperger (Invited speaker), Tobias Jung (Autor*in), Tom Heinze (Autor*in), Tanja Schwerdtle (Autor*in), Annika Höhn (Autor*in) & Tilman Grune (Autor*in)

5 Juni 2024

Aktivität: VorträgeVortragScience to Science


Diet Enriched with Epoxidized Triacylglycerols Induces Inflammatory Responses in the Gastrointestinal Tract of Mice

Magdalena Osowiecka (Vortragende*r), Yifan Bao (Autor*in), Matthias Strauß (Autor*in), Christiane Ott (Autor*in), Daniela Krievda (Autor*in), Richard Bleyer (Autor*in), Yury Lesdov (Autor*in), Sergio Armentia Matheu (Autor*in), Nuno Maulide (Autor*in), Tilman Grune (Autor*in) & Marc Pignitter (Autor*in)

28 Apr. 2024

Aktivität: VorträgeVortragScience to Science


Gastrointestinal Inflammation induced by a Diet Supplemented with Epoxidized Triacylglycerols in Mice

Magdalena Osowiecka (Vortragende*r), Yifan Bao (Autor*in), Matthias Strauß (Autor*in), Christiane Ott (Autor*in), Daniela Krievda (Autor*in), Richard Bleyer (Autor*in), Yury Lesdov (Autor*in), Sergio Armentia Matheu (Autor*in), Nuno Maulide (Autor*in), Tilman Grune (Autor*in) & Marc Pignitter (Autor*in)

3 Apr. 2024

Aktivität: VorträgeVortragScience to Science


Proteolysis in metabolic diseases and aging

Tilman Grune (Vortragende*r)

6 Juni 2023

Aktivität: VorträgeVortragScience to Science


Does density gradient separation after SEC remove lipoprotein miRNAs and increase the yield of EV associated miRNAs?

Agnes Mistlberger-Reiner (Invited speaker), Lukas Kofler (Autor*in), Johanna Fleck (Autor*in), Johannes Österreicher (Autor*in), Susanna Skalichky (Autor*in), Marianne Pultar (Autor*in), Wolfgang Holnthoner (Autor*in), Matthias Hackl (Autor*in) & Tilman Grune (Autor*in)

28 Sept. 2022

Aktivität: VorträgeVortragScience to Science


Institut für Physiologische Chemie

Josef-Holaubek-Platz 2 (UZA II)
1090 Wien
Zimmer: 2B578

tilman.grune@univie.ac.at