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[Zurück]

o. Univ.-Prof. Dr. Dr. Bernhard Keppler

T: +43-1-4277-52602

bernhard.keppler@univie.ac.at

Sommersemester 2024

270011 SE Erstellen der Bachelorarbeit A - Organische / Bioanorganische / Biologische / Biophysikalische Chemie

270012 PR Wahlfachpraktikum A (Bachelormodul) - Organische/Bioanorganische/Biologische/Biophysikalische Chemie

270165 VO Chemie der Aktinide

270186 PR Praktikum Koordinationschemie

270304 PR Praktikum Bioanorganische Chemie

270318 EX Exkursionen in die chemisch-produzierende Großindustrie

530029 SE Strategien zur Entwicklung tumorhemmender Metallkomplexe - für Master- und Doktoratsstudierende des Instituts

Wintersemester 2023

270011 SE Erstellen der Bachelorarbeit A - Organische / Bioanorganische / Biologische / Biophysikalische Chemie

270012 PR Wahlfachpraktikum A (Bachelormodul) - Organische/Bioanorganische/Biologische/Biophysikalische Chemie

270186 PR Praktikum Koordinationschemie

270304 PR Praktikum Bioanorganische Chemie

530028 SE Aktuelle Aspekte der Koordinationschemie - für DissertantInnen

Sommersemester 2023

270011 SE Erstellen der Bachelorarbeit A - Organische / Bioanorganische / Biologische / Biophysikalische Chemie

270012 PR Wahlfachpraktikum A (Bachelormodul) - Organische/Bioanorganische/Biologische/Biophysikalische Chemie

270126 UE Anorganisch-chemisches Praktikum

270165 VO Chemie der Aktinide

270186 PR Praktikum Koordinationschemie

270254 SE Strategien zur Entwicklung tumorhemmender Metallkomplexe - für Master- und Doktoratsstudierende des Instituts

270304 PR Praktikum Bioanorganische Chemie

270318 EX Exkursionen in die chemisch-produzierende Großindustrie

Pósa, V., Federa, A., Cseh, K., Wenisch, D., Spengler, G., May, N. V., Lihi, N., Samu, G. F., Jakupec, M. A., Keppler, B. K., Kowol, C. R., & Enyedy, É. A. (2024). A Comparative Study on the Complexation of the Anticancer Iron Chelator VLX600 with Essential Metal Ions. Inorganic Chemistry, 63(5), 2401-2417. https://doi.org/10.1021/acs.inorgchem.3c03259

Happl, B., Balber, T., Heffeter, P., Denk, C., Welch, J. M., Köster, U., Alliot, C., Bonraisin, A. C., Brandt, M., Haddad, F., Sterba, J. H., Kandioller, W., Mitterhauser, M., Hacker, M., Keppler, B. K., & Mindt, T. L. (2024). Synthesis and preclinical evaluation of BOLD-100 radiolabeled with ruthenium-97 and ruthenium-103. Dalton Transactions. https://doi.org/10.1039/d4dt00118d

Kastner, A., Mendrina, T., Babu, T., Karmakar, S., Poetsch, I., Berger, W., Keppler, B. K., Gibson, D., Heffeter, P., & Kowol, C. R. (2023). Stepwise optimization of tumor-targeted dual-action platinum(iv)-gemcitabine prodrugs. Inorganic Chemistry Frontiers, 11(2), 534-548. https://doi.org/10.1039/d3qi02032k

Baier, D., Mendrina, T., Schoenhacker-Alte, B., Pirker, C., Mohr, T., Rusz, M., Regner, B., Schaier, M., Sgarioto, N., Raynal, N. J. M., Nowikovsky, K., Schmidt, W. M., Heffeter, P., Meier-Menches, S. M., Koellensperger, G., Keppler, B. K., & Berger, W. (2023). The Lipid Metabolism as Target and Modulator of BOLD-100 Anticancer Activity: Crosstalk with Histone Acetylation. Advanced science, 10(32), [2301939]. https://doi.org/10.1002/advs.202301939

Kastner, A., Schueffl, H., Yassemipour, P. A., Keppler, B. K., Heffeter, P., & Kowol, C. R. (2023). Insertion of (Bioactive) Equatorial Ligands into Platinum(IV) Complexes. Angewandte Chemie - International Edition, 62(46), [e202311468]. https://doi.org/10.1002/anie.202311468

Happl, B., Brandt, M., Balber, T., Benčurová, K., Talip, Z., Voegele, A., Heffeter, P., Kandioller, W., Van der Meulen, N. P., Mitterhauser, M., Hacker, M., Keppler, B. K., & Mindt, T. L. (2023). Synthesis and Preclinical Evaluation of Radiolabeled [¹⁰³Ru]BOLD-100. Pharmaceutics, 15(11), [2626]. https://doi.org/10.3390/pharmaceutics15112626

Maier, T., Wutschitz, J., Gajic, N., Hejl, M., Cseh, K., Mai, S., Jakupec, M. A., Galanski, M. S., & Keppler, B. K. (2023). Not the usual suspect - an unexpected organometallic product during the synthesis of cytotoxic platinum(II) complexes. Dalton Transactions, 52(44), 16326-16335. https://doi.org/10.1039/d3dt01736b

Lerchbammer-Kreith, Y., Hejl, M., Wenisch, D., Jakupec, M. A., Galanski, M. S., & Keppler, B. K. (2023). Cytotoxic Impact of Fluorinated Ligands in Equatorial Position of Trans-Configured Diam(m)inetetracarboxylatoplatinum(IV) Complexes. Inorganics, 11(10), [411]. https://doi.org/10.3390/inorganics11100411

Liu, X., Wenisch, D., Dahlke, P., Jordan, P. M., Jakupec, M. A., Kowol, C. R., Liebing, P., Werz, O., Keppler, B. K., & Weigand, W. (2023). Multi-action platinum(IV) prodrugs conjugated with COX-inhibiting NSAIDs. European Journal of Medicinal Chemistry, 257, [115515]. https://doi.org/10.1016/j.ejmech.2023.115515

Tialiou, A., Athab, Z. H., Woodward, R. T., Biegler, V., Keppler, B. K., Halbus, A. F., Reithofer, M. R., & Chin, J. M. (2023). Fabrication of graded porous structure of hydroxypropyl cellulose hydrogels via temperature-induced phase separation. Carbohydrate Polymers, 315, [120984]. https://doi.org/10.1016/j.carbpol.2023.120984

Matczuk, M., Ruzik, L., Keppler, B. K., & Timerbaev, A. R. (2023). Nanoscale Ion-Exchange Materials: From Analytical Chemistry to Industrial and Biomedical Applications. Molecules, 28(18), [6490]. https://doi.org/10.3390/molecules28186490

Gradwohl, A., Windisch, J., Weissensteiner, M., Keppler, B. K., Kandioller, W., & Jirsa, F. (2023). Extraction of rare earth elements from aqueous solutions using the ionic liquid trihexyltetradecylphosphonium 3-hydroxy-2-naphthoate. Rsc advances, 13(36), 24899-24908. https://doi.org/10.1039/d3ra03967f

Schaier, M., Falcone, E., Prstek, T., Vileno, B., Hager, S., Keppler, B. K., Heffeter, P., Koellensperger, G., Faller, P., & Kowol, C. R. (2023). Human serum albumin as a copper source for anticancer thiosemicarbazones. Metallomics, 15(8), [mfad046]. https://doi.org/10.1093/mtomcs/mfad046

Richstein, R., Eisen, C., Ge, L., Chalermnon, M., Mayer, F., Keppler, B. K., Chin, J. M., & Reithofer, M. R. (2023). NHC stabilized copper nanoparticles via reduction of a copper NHC complex. Chemical Communications, 59(64), 9738-9741. https://doi.org/10.1039/d3cc02745g

Caban, M., Koblmueller, B., Groza, D., Schueffl, H. H., Terenzi, A., Tolios, A., Mohr, T., Mathuber, M., Kryeziu, K., Jaunecker, C., Pirker, C., Keppler, B. K., Berger, W., Kowol, C. R., & Heffeter, P. (2023). A novel EGFR inhibitor acts as potent tool for hypoxia-activated prodrug systems and exerts strong synergistic activity with VEGFR inhibition in vitro and in vivo. Cancer Letters, 565, [216237]. https://doi.org/10.1016/j.canlet.2023.216237

Cseh, K., Berasaluce, I., Fuchs, V., Banc, A., Schweikert, A., Prado-Roller, A., Hejl, M., Wernitznig, D., Koellensperger, G., Jakupec, M. A., Kandioller, W., Malarek, M. S., & Keppler, B. K. (2023). Anticancer Tungstenocenes with a Diverse Set of (O,O–), (O,S–) and (O,N–) Chelates—A Detailed Biological Study Using an Improved Evaluation via 3D Spheroid Models. Pharmaceutics, 15(7), [1875]. https://doi.org/10.3390/pharmaceutics15071875

Lerchbammer-Kreith, Y., Hejl, M., Sommerfeld, N. S., Weng-Jiang, X., Odunze, U., Mellor, R. D., Workman, D. G., Jakupec, M. A., Schätzlein, A. G., Uchegbu, I. F., Galanski, M. S., & Keppler, B. K. (2023). Quaternary Ammonium Palmitoyl Glycol Chitosan (GCPQ) Loaded with Platinum-Based Anticancer Agents—A Novel Polymer Formulation for Anticancer Therapy. Pharmaceuticals, 16(7), [1027]. https://doi.org/10.3390/ph16071027

Kastner, A., Mendrina, T., Bachmann, F., Berger, W., Keppler, B. K., Heffeter, P., & Kowol, C. R. (2023). Tumor-targeted dual-action NSAID-platinum(iv) anticancer prodrugs. Inorganic Chemistry Frontiers, 10(14), 4126-4138. https://doi.org/10.1039/d3qi00968h

Szuplewska, A., Sikorski, J., Matczuk, M., Ruzik, L., Keppler, B. K., Timerbaev, A. R., & Jarosz, M. (2023). Enhanced edible plant production using nano-manganese and nano-iron fertilizers: Current status, detection methods and risk assessment. Plant Physiology and Biochemistry, 199, [107745]. https://doi.org/10.1016/j.plaphy.2023.107745

Lerchbammer-Kreith, Y., Hejl, M., Vician, P., Jakupec, M. A., Berger, W., Galanski, M. S., & Keppler, B. K. (2023). Combination of Drug Delivery Properties of PAMAM Dendrimers and Cytotoxicity of Platinum(IV) Complexes—A More Selective Anticancer Treatment? Pharmaceutics, 15(5), [1515]. https://doi.org/10.3390/pharmaceutics15051515